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使用蒙特卡罗方法在配备有圆形圆锥体的 Elekta Axesse 直线加速器中确定几种有源探测器的小射野修正因子。

Small field correction factors determination for several active detectors using a Monte Carlo method in the Elekta Axesse linac equipped with circular cones.

机构信息

Department of Radiotherapy, Universitair Ziekenhuis Brussel, Vrije Universiteit Brussel, Brussels, Belgium. Author to whom any correspondence should be addressed.

出版信息

Phys Med Biol. 2019 Jun 5;64(11):11NT01. doi: 10.1088/1361-6560/ab1f26.

Abstract

A Monte Carlo (MC) method was used to determine small field output correction factors for several active detectors (Exradin A16, Exradin A26, PTW microLion, PTW microDiamond, Exradin W1 and IBA RAZOR) for an Elekta Axesse linac equipped with circular cones. MC model of the linac was built with the GamBet software, using the Penelope code system. The dose-to-water simulation for each cone, ranging from 5 to 30 mm of diameter size, was used to calculate field factors and the results were validated together with Gafchromic EBT3 film. Output factors (OFs) were measured with the active detectors and correction factors were determined using the MC results. The MC simulations agreed with films within 1.2%. OFs measured with Exradin W1 scintillator were in agreement within 0.8% with MC simulations. The Exradin A16 and A26 microchambers under-responded for small fields relative to the MC (-13.1% and  -4.6%, respectively). PTW microLion, IBA RAZOR and PTW microDiamond overestimated the output factor for the smallest field (+3.9%, +5.4 and  +7.1%, respectively). The present study pointed out that it is crucial to apply the appropriate correction factors in order to provide accurate measurements in small beams geometry. The results showed that the Exradin W1 can be used for very small field dosimetry without correction factors, which shall be contrariwise employed for other detectors.

摘要

采用蒙特卡罗(MC)方法确定了几种有源探测器(Exradin A16、Exradin A26、PTW microLion、PTW microDiamond、Exradin W1 和 IBA RAZOR)在配备圆形射野挡块的 Elekta Axesse 直线加速器中小野输出校正因子。使用 Penelope 代码系统的 GamBet 软件建立了直线加速器的 MC 模型。对每个直径从 5 到 30mm 的射野挡块进行水模剂量模拟,以计算射野因子,并用 Gafchromic EBT3 胶片验证结果。使用有源探测器测量输出因子(OFs),并使用 MC 结果确定校正因子。MC 模拟结果与胶片的误差在 1.2%以内。Exradin W1 闪烁体测量的 OFs 与 MC 模拟结果的误差在 0.8%以内。与 MC 相比,Exradin A16 和 A26 微室在小射野时低估了输出因子(分别为-13.1%和-4.6%)。PTW microLion、IBA RAZOR 和 PTW microDiamond 对最小射野的输出因子高估(分别为+3.9%、+5.4%和+7.1%)。本研究指出,为了在小射野几何中提供准确的测量,应用适当的校正因子至关重要。结果表明,Exradin W1 可在无需校正因子的情况下用于非常小的射野剂量测量,而其他探测器则需要使用校正因子。

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