Department for Dosimetry and Quality of Radiological Procedures, Institute of Oncology Ljubljana, Zaloška 2, 1000, Ljubljana, Slovenia.
Medical Physics Service, North Estonia Medical Centre, J. Sütiste tee 19, 13419, Tallinn, Estonia.
Med Phys. 2019 Feb;46(2):944-963. doi: 10.1002/mp.13318. Epub 2018 Dec 24.
The goal of this work is to provide a large and consistent set of data for detector-specific output correction factors, , for small static fields for seven solid-state detectors and to determine field output factors, , using EBT3 radiochromic films and W1 plastic scintillator as reference detectors on two different linear accelerators and four megavoltage photon beams. Consistent measurement conditions and recommendations given in the International Code of Practice TRS-483 for small-field dosimetry were followed throughout the study.
were determined on two linacs, Elekta Versa HD and Varian TrueBeam, for 6 and 10 MV beams with and without flattening filter and for nine fields ranging from 0.5 × 0.5 cm to 10 × 10 cm . Signal readings obtained with EBT3 radiochromic films and W1 plastic scintillator were fitted by an analytical function. Volume averaging correction factors, determined from two-dimensional (2D) dose matrices obtained with EBT3 films and fitted to bivariate Gaussian function, were used to correct measured signals. were determined empirically for six diodes, IBA SFD, IBA Razor, PTW 60008 P, PTW 60012 E, PTW 60018 SRS, and SN EDGE, and a PTW 60019 microDiamond detector.
Field output factors and detector-specific are presented in the form of analytical functions as well as in the form of discrete values. It is found that in general, for a given linac, small-field output factors need to be determined for every combination of beam energy and filtration (WFF or FFF) and field size as the differences between them can be statistically significant (P < 0.05). For different beam energies, the present data for are found to differ significantly (P < 0.05) from the corresponding data published in TRS-483 mostly for the smallest fields (<1.5 cm). For the PTW microDiamond detector, statistically significant differences (P < 0.05) between values were found for all investigated beams on an Elekta Versa HD linac for field sizes 0.5 × 0.5 cm and 0.8 × 0.8 cm . Significant differences in between beams of a given energy but with and without flattening filters are found for measurements made in small fields (<1.5 cm) at a given linac. Differences in are also found when measurements are made at different linacs using the same beam energy filtration combination; for the PTW microDiamond detector, these differences were found to be around 6% and were considered as significant.
Selection of two reference detectors, EBT3 films and W1 plastic scintillator, and use of an analytical function, is a novel approach for the determination of for small static fields in megavoltage photon beams. Large set of data for seven solid-state detectors and four beam energies determined on two linacs by a single group of researchers can be considered a valuable supplement to the literature and the TRS-483 dataset.
本工作的目的是为 7 种固体探测器提供大而一致的小静态场探测器特定输出修正因子 数据集,并使用 EBT3 光致变色胶片和 W1 塑料闪烁体作为参考探测器,在两台不同的直线加速器和 4 个兆伏光子束上确定场输出因子 。在整个研究过程中,遵循了国际辐射单位与测量委员会 TRS-483 小型场剂量学中的建议和规范。
在两台直线加速器 Elekta Versa HD 和 Varian TrueBeam 上,对 6 和 10 MV 射线进行了研究,包括有无均整滤波器的情况,以及 9 个从 0.5×0.5 cm 到 10×10 cm 的场。使用 EBT3 光致变色胶片和 W1 塑料闪烁体获得的信号读数通过解析函数进行拟合。使用从 EBT3 胶片获得的二维(2D)剂量矩阵确定的体积平均修正因子,并使用双变量高斯函数拟合,用于修正测量信号。对六个二极管,IBA SFD、IBA Razor、PTW 60008 P、PTW 60012 E、PTW 60018 SRS 和 SN EDGE,以及一个 PTW 60019 微金刚石探测器,通过经验确定了 。
给出了场输出因子和探测器特定 的解析函数形式和离散值形式。结果表明,一般来说,对于给定的直线加速器,需要为每个射线能量和过滤(WFF 或 FFF)以及射野大小组合确定小射野输出因子,因为它们之间的差异在统计学上可能是显著的(P<0.05)。对于不同的射线能量,本研究中的 数据与 TRS-483 中相应的数据存在显著差异(P<0.05),主要是对于最小的射野(<1.5 cm)。对于 PTW 微金刚石探测器,在 Elekta Versa HD 直线加速器上,对于所有研究的射线,在 0.5×0.5 cm 和 0.8×0.8 cm 的射野大小下, 值存在统计学显著差异(P<0.05)。在给定的直线加速器上,对于给定能量的射线,但有无均整滤波器的情况下,在小射野(<1.5 cm)中进行的测量,发现 之间存在显著差异。在使用相同射线能量过滤组合在不同直线加速器上进行测量时,也发现了 的差异;对于 PTW 微金刚石探测器,这些差异约为 6%,被认为是显著的。
选择两个参考探测器,EBT3 胶片和 W1 塑料闪烁体,并使用解析函数,是一种用于确定兆伏光子束中小静态场的 的新方法。由一组研究人员在两台直线加速器上确定的 7 种固体探测器和 4 种射线能量的大型 数据集,可以被认为是对文献和 TRS-483 数据集的有价值的补充。