Mester de Parajd L, Mester de Parajd M
Acta Leprol. 1986 Jul-Sep;4(3):363-72.
We are interested for other human metabolites than desoxyfructo-serotonin (DFS), showing antileprosy activity. This is the case of desoxyfructo-5-hydroxytryptophan and of some liposoluble derivatives of DFS. The time of resorption and penetration into M. leprae infected tissue, is very different for these metabolites. For this reason the simultaneous application of these compounds may represent some advantage in the treatment of multibacillar form of leprosy. The use of DFS together with the antileprosy diet "NAL" have the supplementary advantage to stabilize the DFS level in the serum during the treatment.
我们对除脱氧果糖血清素（DFS）之外的其他具有抗麻风活性的人体代谢物感兴趣。脱氧果糖5-羟色氨酸以及DFS的一些脂溶性衍生物就是这种情况。这些代谢物在被麻风杆菌感染的组织中的吸收和渗透时间有很大差异。因此，同时应用这些化合物可能在治疗多菌型麻风病方面具有一定优势。将DFS与抗麻风病饮食“NAL”一起使用还有一个额外的优势，即能在治疗期间稳定血清中的DFS水平。
