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[脱氧果糖血清素对麻风分枝杆菌的作用。治疗一年后人体活检标本接种于小鼠的结果]

[Action of desoxyfructo-serotonin on Mycobacterium leprae. Results of inoculation of human biopsy specimens in the mouse after a year of treatment].

作者信息

Ferracci C, Baquillon G, Pattyn S R

出版信息

Acta Leprol. 1983 Oct-Dec;1(4):233-5.

PMID:6377799
Abstract

M. leprae, extracted from cutaneous biopsies of 4 out of 7 patients treated with DFS during one year at doses of 1000 to 1500 mg/day were injected in mouse foot pads. Bacterial multiplication was observed in each case. The purely bacteriostatic activity of DFS for M. leprae, previously observed in mice, is thus confirmed. The eventual place of DFS in the therapy of leprosy is discussed.

摘要

从7例接受一年二苯砜治疗（剂量为每日1000至1500毫克）的患者中，取4例患者的皮肤活检组织提取麻风杆菌，并注射到小鼠足垫中。在每例中均观察到细菌增殖。从而证实了先前在小鼠中观察到的二苯砜对麻风杆菌的单纯抑菌活性。本文讨论了二苯砜在麻风病治疗中的最终地位。

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Acta Leprol. 1983 Oct-Dec;1(4):233-5.
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