Tommasini Matteo, Zanchi Chiara, Lucotti Andrea, Bombelli Alessandro, Villa Nicolò S, Casazza Marina, Ciusani Emilio, de Grazia Ugo, Santoro Marco, Fazio Enza, Neri Fortunato, Trusso Sebastiano, Ossi Paolo M
Dipartimento di Chimica, Materiali e Ingegneria Chimica "G. Natta", Politecnico di Milano, Piazza Leonardo da Vinci 32, 20133 Milano, Italy.
Dipartimento di Energia, Politecnico di Milano, Via Ponzio 34/3, 20133 Milano, Italy.
Nanomaterials (Basel). 2019 May 1;9(5):677. doi: 10.3390/nano9050677.
The synthesis by pulsed laser ablation and the characterization of both the surface nanostructure and the optical properties of noble metal nanoparticle-based substrates used in Surface Enhanced Raman Spectroscopy are discussed with reference to application in the detection of anti-epileptic drugs. Results on two representative drugs, namely Carbamazepine and Perampanel, are critically addressed.
讨论了通过脉冲激光烧蚀合成用于表面增强拉曼光谱的基于贵金属纳米颗粒的基底的表面纳米结构和光学性质,并参考了其在抗癫痫药物检测中的应用。重点阐述了两种代表性药物,即卡马西平和吡仑帕奈的检测结果。