动静脉畸形中的脑血流动力学：单光子发射计算机断层扫描评估
Cerebral hemodynamics in arteriovenous malformations: evaluation by single-photon emission CT.
作者信息
Takeuchi S, Kikuchi H, Karasawa J, Naruo Y, Hashimoto K, Nishimura T, Kozuka T, Hayashi M
出版信息
AJNR Am J Neuroradiol. 1987 Mar-Apr;8(2):193-7.
Cerebral hemodynamics in six patients with supratentorial arteriovenous malformations (AVMs) were studied by using single-photon emission CT with three types of radioactive isotopes: N-isopropyl-p-[123I] iodoamphetamine, 81mKr, and 99mTc-RBC in order to determine the local cerebral blood flow and blood volume associated with these malformations. The AVMs were shown to have high flow while other areas of the brain, including the contralateral hemisphere, had variable areas of diminished perfusion. There was increased blood volume in the regions of AVMs, and poor but evenly distributed blood volume in the other regions. CO2 reactivity during hypocapnia was preserved throughout the brain except for the region of the AVMs. In large AVMs, the ischemic state surrounding the nidus was considered to be caused mainly by the cerebral steal phenomenon.
为了确定与幕上动静脉畸形（AVM）相关的局部脑血流量和血容量，我们使用单光子发射计算机断层扫描（SPECT）及三种放射性同位素：N-异丙基-p-[123I]碘安非他明、81m氪和99m锝标记红细胞，对6例幕上AVM患者的脑血流动力学进行了研究。结果显示，AVM具有高血流量，而包括对侧半球在内的大脑其他区域存在灌注减少的不同区域。AVM区域血容量增加，其他区域血容量虽少但分布均匀。除AVM区域外，全脑在低碳酸血症期间的二氧化碳反应性得以保留。在大型AVM中，病灶周围的缺血状态被认为主要是由脑盗血现象引起的。
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