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两名脑膜瘤患者经单光子发射计算机断层扫描(SPECT)使用N-异丙基-p-碘安非他明(I-123)显示为高摄取。

Two patients with meningioma visualized as high uptake by SPECT with N-isopropyl-p-iodo-amphetamine (I-123).

作者信息

Nishimura T, Hayashida K, Uehara T, Imakita S, Hashimoto K, Naruo Y, Kikuchi H

机构信息

Department of Radiology, National Cardiovascular Center, Osaka, Japan.

出版信息

Neuroradiology. 1988;30(4):351-4. doi: 10.1007/BF00328188.

DOI:10.1007/BF00328188
PMID:3262837
Abstract

It has been reported that brain tumors show decreased IMP uptake, however, we encountered two cases of meningioma which had initially increased IMP uptake. SPECT was performed at 30 min, 2 hr and 6 hr after intravenous administration of IMP (3 mCi). The delayed images (2 and 6 h) showed decreased IMP uptake. These were convexity and parasagittal meningiomas which had tumor stains at angiography. Although the mechanism of IMP uptake in brain tumor is still unclear, this finding should be considered in the interpretation of IMP-SPECT.

摘要

据报道,脑肿瘤显示IMP摄取减少,然而,我们遇到了两例最初IMP摄取增加的脑膜瘤病例。在静脉注射IMP(3毫居里)后30分钟、2小时和6小时进行单光子发射计算机断层扫描(SPECT)。延迟图像(2小时和6小时)显示IMP摄取减少。这些是在血管造影时有肿瘤染色的凸面和矢状旁脑膜瘤。尽管脑肿瘤中IMP摄取的机制仍不清楚,但在解释IMP-SPECT时应考虑这一发现。

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1
Two patients with meningioma visualized as high uptake by SPECT with N-isopropyl-p-iodo-amphetamine (I-123).两名脑膜瘤患者经单光子发射计算机断层扫描(SPECT)使用N-异丙基-p-碘安非他明(I-123)显示为高摄取。
Neuroradiology. 1988;30(4):351-4. doi: 10.1007/BF00328188.
2
[Regional cerebral blood flow images of single photon emission computed tomography by N-isopropyl-p-[I-123] iodoamphetamine in patients with brain tumor].[采用 N-异丙基-p-[I-123] 碘安非他明的单光子发射计算机断层扫描对脑肿瘤患者进行的局部脑血流成像]
No To Shinkei. 1987 Jul;39(7):687-93.
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Dynamic SPECT with iodine-123 IMP in meningiomas.
J Nucl Med. 1988 Oct;29(10):1627-32.
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[Single photon emission computed tomography (SPECT) with N-isopropyl-p-(123I) iodoamphetamine in partial epilepsy--evaluation of delayed image].[单光子发射计算机断层扫描(SPECT)联合N-异丙基-p-(123I)碘安非他明在部分性癫痫中的应用——延迟图像评估]
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[Increased iodine-123 amphetamine (IMP) uptake in two cases of meningioma].[两例脑膜瘤中碘-123安非他明(IMP)摄取增加]
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Usefulness of dual isotope I-IMP and Tl SPECT for the diagnosis of primary central nervous system lymphoma and glioblastoma.双同位素 I-IMP 和 Tl SPECT 对原发性中枢神经系统淋巴瘤和胶质母细胞瘤的诊断价值。
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Development of I-123-labeled amines for brain studies: localization of I-123 iodophenylalkyl amines in rat brain.
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123I-间碘苄胍单光子发射计算机断层扫描在脑肿瘤中的初步研究
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Cerebral blood-flow tomography: xenon-133 compared with isopropyl-amphetamine-iodine-123: concise communication.脑血流断层扫描:氙-133与异丙基安非他明-碘-123的比较:简要通讯
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Local cerebral blood flow and partition coefficients measured in cerebral astrocytomas of different grades of malignancy.在不同恶性程度的脑星形细胞瘤中测量局部脑血流量和分配系数。
Surg Neurol. 1984 Feb;21(2):125-31. doi: 10.1016/0090-3019(84)90329-x.
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Decreased accumulation of isopropyl-lodoamphetamine (I-123) in brain tumors.脑肿瘤中异丙基-碘安非他明(I-123)的蓄积减少。
J Nucl Med. 1981 Dec;22(12):1081-3.
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Cerebral blood flow studies with 123iodine-labelled amines.
Lancet. 1983 Jun 18;1(8338):1348-52. doi: 10.1016/s0140-6736(83)92137-2.
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Cerebral dynamics of N-isopropyl-(123I)p-iodoamphetamine.
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Cerebral hemodynamics in arteriovenous malformations: evaluation by single-photon emission CT.动静脉畸形中的脑血流动力学:单光子发射计算机断层扫描评估
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