Department of Obstetrics and Gynecology, Stellenbosch University and Tygerberg Academic Hospital, Cape Town, South Africa.
Department of Obstetrics and Gynecology, Amsterdam UMC, Vrije Universiteit Amsterdam, Amsterdam, the Netherlands.
Int J Gynaecol Obstet. 2019 Jul;146(1):103-109. doi: 10.1002/ijgo.12837. Epub 2019 May 25.
To determine incidence, risk indicators, and outcomes of emergency peripartum hysterectomy (EPH) in Metro East, Cape Town, South Africa.
A population-based district-wide prospective descriptive study of EPH in public hospitals from November 2014 to November 2015. Women were enrolled by using the WHO maternal near miss tool and followed until discharge. EPH was defined as hemorrhage or infection leading to hysterectomy during pregnancy or within 42 days of delivery.
Fifty-nine women experienced EPH with an overall incidence of 14.3 per 10 000 women: 32 procedures were for postpartum hemorrhage, 27 for puerperal sepsis. Two women died: one from sepsis; one from hemorrhage. Overall, 51 (86%) women delivered by cesarean, and 23/51 (45%) by repeat cesarean. As compared with hemorrhage, EPH for sepsis involved older women (mean age, 31.5 vs 24.4 years) and those with higher gravidity (median, 3 vs 1), and was associated with longer hospital admission (median, 11.5 vs 4 days), with occurrence later postpartum (median, 8 vs 0 days), and more frequently with complications.
The incidence of EPH for sepsis was higher than previously reported. Repeat cesarean was strongly associated with EPH. Clinical characteristics of sepsis-related EPH compared unfavorably with those of hemorrhage-related EPH.
在南非开普敦的 Metro East,确定紧急围产期子宫切除术(EPH)的发生率、风险指标和结局。
这是一项 2014 年 11 月至 2015 年 11 月期间在公立医院进行的基于人群的全区前瞻性描述性研究,使用世界卫生组织孕产妇接近死亡工具纳入 EPH 患者,并随访至出院。EPH 的定义为妊娠期间或分娩后 42 天内因出血或感染导致的子宫切除术。
共有 59 名妇女经历了 EPH,总发生率为每 10 000 名妇女 14.3 例:32 例为产后出血,27 例为产褥期败血症。有 2 名妇女死亡:1 例死于败血症;1 例死于出血。总体而言,51 名(86%)妇女行剖宫产分娩,其中 23 名(45%)为再次剖宫产。与出血相比,EPH 因败血症而发生的患者年龄更大(平均年龄 31.5 岁比 24.4 岁),孕次更高(中位数 3 次比 1 次),住院时间更长(中位数 11.5 天比 4 天),产后时间更晚(中位数 8 天比 0 天),且更常发生并发症。
EPH 因败血症的发生率高于先前报道。再次剖宫产与 EPH 强烈相关。与出血相关的 EPH 相比,败血症相关的 EPH 临床特征较差。