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Interferon-Gamma test for the detection of Mycobacterium tuberculosis complex infection in Macaca mulatta and other non-human primates.用于检测恒河猴及其他非人灵长类动物结核分枝杆菌复合群感染的干扰素-γ检测
J Med Primatol. 2019 Aug;48(4):260-263. doi: 10.1111/jmp.12420. Epub 2019 May 6.
2
TB diagnosis in non-human primates: comparison of two interferon-gamma assays and the skin test for identification of Mycobacterium tuberculosis infection.非人灵长类动物的结核病诊断：两种干扰素-γ检测方法与结核菌素皮肤试验用于鉴定结核分枝杆菌感染的比较
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Tuberculosis (TB) outbreak in a closed Aotus monkey breeding colony: Epidemiology, diagnosis and TB screening using antibody and interferon-gamma release testing.封闭的食蟹猴饲养群中暴发结核病（TB）：使用抗体和干扰素-γ释放试验进行的流行病学、诊断和 TB 筛查。
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Comparison of lymphocyte stimulation and tuberculin skin reactivity in Mycobacterium bovis-infected Macaca mulatta.牛分枝杆菌感染的恒河猴中淋巴细胞刺激与结核菌素皮肤反应性的比较。
Am J Vet Res. 1975 May;36(5):699-701.
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An interferon-gamma release assay for the diagnosis of the Mycobacterium bovis infection in white rhinoceros (Ceratotherium simum).一种用于诊断白犀牛（犀科白犀属）牛分枝杆菌感染的干扰素-γ释放试验。
Vet Immunol Immunopathol. 2019 Nov;217:109931. doi: 10.1016/j.vetimm.2019.109931. Epub 2019 Aug 15.

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The new gamma interferon (IFN-γ) algorithm for tuberculosis diagnosis in cynomolgus macaques.食蟹猴结核病诊断的新型γ干扰素（IFN-γ）算法
PLoS One. 2024 Dec 16;19(12):e0302349. doi: 10.1371/journal.pone.0302349. eCollection 2024.
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Tuberculosis detection in nonhuman primates is enhanced by use of testing algorithms that include an interferon-γ release assay.在非人类灵长类动物中，通过使用包括干扰素-γ释放试验在内的检测算法，可提高结核病检测的效果。
Am J Vet Res. 2021 Nov 10;83(1):15-22. doi: 10.2460/ajvr.21.08.0124.

本文引用的文献

1
QuantiFERON-TB Gold In-Tube test in active tuberculosis patients and healthy adults.活动性肺结核患者和健康成年人的全血γ-干扰素释放试验（QuantiFERON-TB Gold In-Tube test）。
Rev Inst Med Trop Sao Paulo. 2018 Oct 22;60:e56. doi: 10.1590/S1678-9946201860056.
2
Tuberculosis (TB) outbreak in a closed Aotus monkey breeding colony: Epidemiology, diagnosis and TB screening using antibody and interferon-gamma release testing.封闭的食蟹猴饲养群中暴发结核病（TB）：使用抗体和干扰素-γ释放试验进行的流行病学、诊断和 TB 筛查。
Comp Immunol Microbiol Infect Dis. 2018 Jun;58:1-10. doi: 10.1016/j.cimid.2018.06.007. Epub 2018 Jun 15.
3
Outbreak of Tuberculosis in a Colony of Rhesus Monkeys (Macaca mulatta) after Possible Indirect Contact with a Human TB Patient.恒河猴（猕猴）群体中可能因与一名人类结核病患者间接接触而爆发结核病
J Comp Pathol. 2015 Aug-Oct;153(2-3):81-91. doi: 10.1016/j.jcpa.2015.05.006. Epub 2015 Jul 10.
4
Modeling tuberculosis in nonhuman primates.在非人灵长类动物中建立结核病模型。
Cold Spring Harb Perspect Med. 2014 Sep 11;4(12):a018564. doi: 10.1101/cshperspect.a018564.
5
A naturally occurring outbreak of tuberculosis in a group of imported cynomolgus monkeys (Macaca fascicularis).一群进口食蟹猴（猕猴）中自然发生的结核病疫情。
J Am Assoc Lab Anim Sci. 2010 Mar;49(2):221-5.
6
New approaches to tuberculosis surveillance in nonhuman primates.非人灵长类动物结核病监测的新方法。
ILAR J. 2008;49(2):170-8. doi: 10.1093/ilar.49.2.170.
7
Diagnosis of Mycobacterium bovis infection in cattle by use of the gamma-interferon (Bovigam) assay.使用γ-干扰素（Bovigam）检测法诊断牛的牛分枝杆菌感染
Vet Microbiol. 2006 Feb 25;112(2-4):171-9. doi: 10.1016/j.vetmic.2005.11.029.
8
Diagnosis of tuberculosis in macaques, using whole-blood in vitro interferon-gamma (PRIMAGAM) testing.使用全血体外干扰素-γ（PRIMAGAM）检测法诊断猕猴结核病。
Comp Med. 2004 Feb;54(1):86-92.

用于检测恒河猴及其他非人灵长类动物结核分枝杆菌复合群感染的干扰素-γ检测

Interferon-Gamma test for the detection of Mycobacterium tuberculosis complex infection in Macaca mulatta and other non-human primates.

作者信息

Yee JoAnn L, Prongay Kamm, Miles Brodie, Smedley Jeremy, Hansen Scott G, Axthelm Michael K, Ardeshir Amir, Van Rompay Koen K A, Timmel Gregory, Roberts Jeffrey A

机构信息

California National Primate Research Center, University of California, Davis, California.

Oregon National Primate Research Center, Oregon Health Sciences University, Beaverton, Oregon.

出版信息

J Med Primatol. 2019 Aug;48(4):260-263. doi: 10.1111/jmp.12420. Epub 2019 May 6.

DOI:10.1111/jmp.12420
PMID:31056769
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC7012381/
Abstract

We have formatted an assay to detect Mycobacterium tuberculosis complex infections of non-human primates. Commercially available reagents were used to elicit a specific immune response that was measured by interferon-gamma release. Initial evaluation using blood samples from Rhesus macaques experimentally infected with M tuberculosis distinguished infected versus uninfected animals.

摘要

我们已经设计了一种检测非人灵长类动物结核分枝杆菌复合群感染的检测方法。使用市售试剂引发特定免疫反应，该反应通过γ-干扰素释放来测量。使用来自实验性感染结核分枝杆菌的恒河猴的血样进行的初步评估区分了感染动物和未感染动物。