Nair Manisha, Gurunathan Deepa
Department of Pedodontics, Saveetha Dental College, Saveetha Institute of Medical and Technical Sciences, Poonamalee High Road, Chennai, Tamil Nadu, India.
J Anaesthesiol Clin Pharmacol. 2019 Jan-Mar;35(1):65-69. doi: 10.4103/joacp.JOACP_73_18.
Topical anesthetic agents are widely used in the field of pediatric dentistry to reduce pain and apprehension during administration of local anesthesia. Various topical anesthetic agents are available, among which the most commonly used ones are lignocaine and benzocaine. Hence we planned this study to compare and evaluate the effectiveness of topical anesthesia on needle insertion pain during administration of inferior alveolar nerve block.
This double blind clinical study included 30 children of 4-8 years of age who were divided equally into two groups: Group A-2% lignocaine hydrochloride gel (Lox 2%) and Group B-20% benzocaine gel (ProGel-B). The intervention involved assessment of pain perception by the child during administration of inferior alveolar nerve block. The child's pain assessment was done using modified Wong-Baker pain rating scale. The ratings were subjected to statistical analysis.
In Group A, 6.7% ( = 1) showed slight pain, 66.7% ( = 10) showed moderate pain, and 26.7% ( = 4) showed severe pain. In Group B, 46.7% ( = 7) showed no pain, 46% ( = 7) showed slight pain, and 6.7% ( = 1) showed moderate pain on needle insertion. ( value -0.000).
This study demonstrates that there is a highly significant difference between the topical anesthetic effectiveness of 2% lignocaine and 20% benzocaine on needle insertion pain in inferior alveolar nerve block. Twenty percent benzocaine showed better results than 2% lignocaine in reducing the needle insertion pain.
局部麻醉剂在儿童牙科领域被广泛使用,以减轻局部麻醉给药过程中的疼痛和焦虑。有多种局部麻醉剂可供使用,其中最常用的是利多卡因和苯佐卡因。因此,我们计划开展本研究,以比较和评估局部麻醉在下牙槽神经阻滞给药过程中对针刺疼痛的有效性。
这项双盲临床研究纳入了30名4至8岁的儿童,他们被平均分为两组:A组——2%盐酸利多卡因凝胶(Lox 2%)和B组——20%苯佐卡因凝胶(ProGel-B)。干预措施包括评估儿童在下牙槽神经阻滞给药过程中的疼痛感知。使用改良的面部表情疼痛评分量表对儿童的疼痛进行评估。对评分进行统计分析。
在A组中,6.7%(n = 1)表现为轻微疼痛,66.7%(n = 10)表现为中度疼痛,26.7%(n = 4)表现为重度疼痛。在B组中,46.7%(n = 7)在针刺时无疼痛,46%(n = 7)表现为轻微疼痛,6.7%(n = 1)表现为中度疼痛。(P值 -0.000)。
本研究表明,2%利多卡因和20%苯佐卡因在下牙槽神经阻滞针刺疼痛的局部麻醉效果之间存在高度显著差异。20%苯佐卡因在减轻针刺疼痛方面比2%利多卡因效果更好。