Darii Natalia, Pavlovic Milenko, Doroftei Bogdan, Emil Anton
Department of Gynecology, CHU de Charleroi, Montigny-le-Tilleul, Belgium.
Department of Gynecology, Faculty of Medicine, Pontificia Universidad Católica de Chile, Santiago, Chile.
JBRA Assist Reprod. 2019 Oct 14;23(4):430-433. doi: 10.5935/1518-0557.20190002.
Ovarian hyperstimulation syndrome (OHSS) is one of the most serious complications of fertilization (IVF). We present a case of OHSS maintained and aggraved by albumin administration. A 29-year-old woman with severe OHSS was treated with albumin perfusion according to the guidelines. The albumin was administered in order to maintain intravascular oncotic pressure and to reverse the shift of fluid from the intravascular to the third space, but this therapeutic measure resulted in inadvertent maintenance of the syndrome. The treatment of OHSS is a delicate balance between invasive approaches, such as paracentesis, administration of colloids and minimal therapeutic intervention, particularly during pregnancy.
卵巢过度刺激综合征（OHSS）是体外受精（IVF）最严重的并发症之一。我们报告一例因输注白蛋白导致OHSS持续存在并加重的病例。一名29岁患有严重OHSS的女性按照指南接受了白蛋白灌注治疗。输注白蛋白的目的是维持血管内胶体渗透压并逆转液体从血管内向第三间隙的转移，但这一治疗措施却意外地使该综合征持续存在。OHSS的治疗是一种微妙的平衡，涉及侵入性方法（如腹腔穿刺术、输注胶体）和最小限度的治疗干预，尤其是在孕期。
