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[铜绿假单胞菌作为机会性感染的病原体]

[Pseudomonas aeruginosa as the pathogen in opportunistic infections].

作者信息

Dalhoff A

出版信息

Infection. 1987 Jan-Feb;15(1):69-72. doi: 10.1007/BF01646126.

Abstract

Pseudomonas aeruginosa, in spite of being an ubiquitous microorganism, rarely colonizes healthy individuals. Hospitalization, as well as the length of time spent in hospital, significantly increase the rate of colonization, especially in immunocompromized patients. Antibacterial chemotherapy or prophylaxis together with invasive diagnostic procedures favour colonization and infection with P. aeruginosa. Immune deficiencies and adverse interactions of P. aeruginosa with the immune system facilitate infection. Thus, a number of exogenous as well as endogenous factors and their interactions favour infection of patients with P. aeruginosa.

摘要

铜绿假单胞菌尽管是一种广泛存在的微生物,但很少在健康个体中定植。住院以及在医院停留的时间会显著增加定植率,尤其是在免疫功能低下的患者中。抗菌化疗或预防措施以及侵入性诊断程序有利于铜绿假单胞菌的定植和感染。免疫缺陷以及铜绿假单胞菌与免疫系统的不良相互作用会促进感染。因此,许多外源性和内源性因素及其相互作用有利于患者感染铜绿假单胞菌。

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