Department of Veterinary Medical Sciences, University of Bologna, Bologna, Italy.
Istituto Zooprofilattico Sperimentale della Lombardia e dell'Emilia-Romagna 'Bruno Ubertini', Brescia, Italy.
Lett Appl Microbiol. 2019 Aug;69(2):96-99. doi: 10.1111/lam.13168. Epub 2019 Jun 7.
This paper describes for the first time the isolation of Streptococcus lutetiensis in a cat with intestinal lymphoma. The Streptococcus bovis group has undergone significant taxonomic changes over the past two decades and, in 2002, Poyart et al. described two distinct novel species within the genus Streptococcus: Streptococcus lutetiensis and Streptococcus pasteurianus. The bovis group streptococci include commensal species and subspecies or opportunistic pathogens of humans and animals. The cat was referred to the Veterinary Teaching Hospital, University of Bologna for chronic diarrhoea associated with fresh blood. A diagnosis of intestinal lymphoma was advanced. S. lutetiensis was accidentally isolated from the faeces of the cat and identified through MALDI-TOF and 16s rRNA sequencing. The Kirby-Bauer test revealed that the isolate was resistant to enrofloxacin, erythromycin, clindamycin, marbofloxacin and tetracycline. The detection of S. lutetiensis in cat faeces might suggest that it could be a normal inhabitant of cat intestinal tract or that it could be involved in the manifestation of intestinal diseases. Since bacteria belonging to the S. bovis group are considered emerging pathogens, additional research is required to evaluate the role of S. lutetiensis in cats and its role in the transmission of antimicrobial resistance. SIGNIFICANCE AND IMPACT OF THE STUDY: In this study the isolation of Streptococcus lutetiensis from a cat with intestinal lymphoma was described for the first time. An antimicrobial susceptibility test performed by means of the disc diffusion method revealed that the isolate was resistant to enrofloxacin, erythromycin, clindamycin, marbofloxacin and tetracycline. Nowadays the ecological or pathogenetic role of S. lutetiensis in the gut of animals remains unclear but, even if its role as commensal bacterium was confirmed, the presence of multi-resistant S. lutetiensis in cat gut could favour the transmission of antimicrobial resistance to other bacteria.
本文首次描述了在患有肠道淋巴瘤的猫中分离出缓症链球菌。在过去的二十年中，牛链球菌群经历了重大的分类变化，2002 年，Poyart 等人在链球菌属内描述了两种不同的新型物种：缓症链球菌和巴氏链球菌。牛链球菌群链球菌包括共生种和亚种或人类和动物的机会性病原体。该猫因与新鲜血液相关的慢性腹泻被转诊至博洛尼亚大学兽医教学医院。提出了肠道淋巴瘤的诊断。意外地从猫粪便中分离出缓症链球菌，并通过 MALDI-TOF 和 16s rRNA 测序进行鉴定。Kirby-Bauer 测试显示，该分离株对恩诺沙星、红霉素、克林霉素、马波沙星和四环素具有耐药性。在猫粪便中检测到缓症链球菌可能表明它可能是猫肠道的正常居民，也可能与肠道疾病的表现有关。由于属于牛链球菌群的细菌被认为是新兴的病原体，因此需要进一步研究来评估缓症链球菌在猫中的作用及其在传播抗菌耐药性方面的作用。研究的意义和影响：在这项研究中，首次描述了从患有肠道淋巴瘤的猫中分离出缓症链球菌。通过纸片扩散法进行的药敏试验显示，该分离株对恩诺沙星、红霉素、克林霉素、马波沙星和四环素耐药。如今，缓症链球菌在动物肠道中的生态或病原体作用尚不清楚，但即使其作为共生菌的作用得到证实，猫肠道中多耐药性缓症链球菌的存在也可能有利于将抗菌耐药性传播给其他细菌。
