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[利普许茨溃疡,儿科人群中需考虑的一种诊断]

[Ulcer of Lipschütz, a diagnosis to consider in the pediatric population].

作者信息

Arellano Javier, Fuentes Eliseo, Moreno Patricia, Corredoira Yamile

机构信息

Departamento de Dermatología, Sede Centro, Facultad de Medicina, Universidad de Chile.

Servicio de Dermatología, Hospital Clínico San Borja-Arriarán.

出版信息

Arch Argent Pediatr. 2019 Jun 1;117(3):e305-e308. doi: 10.5546/aap.2019.e305.

Abstract

Acute vulvar ulcer or ulcer of Lipschütz corresponds to a rare disease, being usually underdiagnosed. It is characterized by a sudden or acute development of ulcerous and painful lesions in the vulva, vagina and/or perineum, without a previous history of sexual contact in girls and teenagers. Its etiology remains unknown in most cases, although they have been associated with infectious agents. Their study includes the suspicion of sexually transmitted infections, adverse drug reactions, autoimmune diseases and immunosuppression. The ulcerative lesions disappear spontaneously, usually without sequelae or recurrences in the long term. We present the case of an 11-year-old adolescent patient, without sexual initiation, or menarche and who consulted due to a four-day prodromal condition, followed by the acute development of genital ulcers. Its causes, clinical presentation, differential diagnosis and treatment are discussed.

摘要

急性外阴溃疡或利普许茨溃疡是一种罕见疾病,通常诊断不足。其特征是在外阴、阴道和/或会阴突然或急性出现溃疡性疼痛病变,在女童和青少年中无前性接触史。虽然多数病例病因不明,但已发现与感染因素有关。其研究包括怀疑性传播感染、药物不良反应、自身免疫性疾病和免疫抑制。溃疡性病变通常会自行消失,长期来看一般无后遗症或复发。我们报告一例11岁青春期前患者,无性经历及月经初潮,因前驱症状持续四天后急性出现生殖器溃疡前来就诊。文中讨论了其病因、临床表现、鉴别诊断及治疗。

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