Brink E W, Perera W D, Broske S P, Cash R A, Smith J L, Sauberlich H E, Bashor M M
Am J Clin Nutr. 1979 Jan;32(1):84-91. doi: 10.1093/ajcn/32.1.84.
A representative country-wide rural nutrition status survey determined the extent and distribution of vitamin A deficiency in Sri Lanka in children 6 through 71 months of age. Trained paramedical personnel recorded the presence or absence of selected ophthalmological signs and symptoms associated with vitamin A deficiency in 13,450 children. The results of the country-wide clinical survey indicate that a vitamin A deficiency problem of public health importance may exist in two of 15 health areas. Serum vitamin A levels were determined on 346 survey children from two of 15 health areas and compared with clinical findings for these areas. The lowest mean serum vitamin A, 26.3 microgram/100 ml, occurred in children with clinical eye findings. A high prevalence of clinical eye findings, 34%, and the low mean serum vitamin A value, 28.2 microgram/100 ml, were found in the group of chronically undernourished children--children who are less than 90% of their expected height for age. The survey results enabled planned redirection of the distribution of vitamin A capsules to preschool children in Sri Lanka to areas shown to have the highest prevalences of ophthalmological signs and symptoms and/or the highest prevalence of chronic undernutrition.
一项具有代表性的全国农村营养状况调查确定了斯里兰卡6至71个月大儿童维生素A缺乏症的程度和分布情况。训练有素的辅助医务人员记录了13450名儿童中与维生素A缺乏症相关的特定眼科体征和症状的有无。全国临床调查结果表明,15个卫生区域中的两个区域可能存在具有公共卫生重要性的维生素A缺乏问题。对15个卫生区域中两个区域的346名接受调查儿童测定了血清维生素A水平,并将其与这些区域的临床检查结果进行比较。临床眼部检查有异常的儿童血清维生素A平均水平最低,为26.3微克/100毫升。在长期营养不良的儿童组(即身高低于预期年龄身高90%的儿童)中,临床眼部检查异常的患病率很高,达34%,血清维生素A平均水平较低,为28.2微克/100毫升。调查结果使得能够对斯里兰卡学龄前儿童维生素A胶囊的分发进行有计划的调整,将其分发到眼科体征和症状患病率最高和/或慢性营养不良患病率最高的地区。