通过培养基改良减少头孢噻肟耐药铜绿假单胞菌对雅培MS-2假敏感错误的尝试。
Attempted reduction of Abbott MS-2 false-susceptible errors for cefotaxime-resistant Pseudomonas aeruginosa by medium modification.
作者信息
Lander D W, Jungkind D L, Stone L L
出版信息
J Clin Microbiol. 1987 Apr;25(4):732-3. doi: 10.1128/jcm.25.4.732-733.1987.
Abstract
Thirty-five modifications of Abbott MS-2 growth medium were evaluated in an attempt to reduce the high frequency of false-susceptible errors produced by the MS-2 system when testing resistant Pseudomonas aeruginosa against cefotaxime. A hypotonic modification with 0.1% KNO3 reduced the errors from 41 to 20% for 23 resistant isolates. All hypertonic modifications proved unsatisfactory. No modification reduced false-susceptible errors to acceptable clinical levels.
摘要
对雅培MS-2生长培养基的35种改良配方进行了评估，旨在减少MS-2系统在检测耐头孢噻肟的铜绿假单胞菌时产生的高频率假敏感错误。一种含0.1%硝酸钾的低渗改良配方，使23株耐药菌株的错误率从41%降至20%。所有高渗改良配方均未达预期效果。没有一种改良配方能将假敏感错误率降低到可接受的临床水平。
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