ICMR-Regional Medical Research Centre, Bhubaneswar, Odisha, India.
Naba Diganta Primary Care Hospital, Keonjhar, Bhubaneswar, Odisha, India.
Indian Pediatr. 2019 Apr 15;56(4):304-306.
To investigate the distribution and clinical profile of scrub typhus infection among children with acute febrile illness in Odisha.
Children (<15 y) presenting with acute fever (>5 days) in 4 agro-climatic zones from June to November 2017 were evaluated. Patients were screened for malaria, leptospira, dengue, typhoid and scrub typhus. Scrub typhus was confirmed by IgM ELISA and PCR.
Out of 413 cases examined, 48.7% were positive for scrub typhus, and 5.5% of them developed systemic complications. Eschar was found in 17.9% of cases. Five days treatment of Doxycycline and/or Azithromycin was clinically effective against scrub typhus.
Our study highlights that scrub typhus is one of the causes of high morbidity in children during rainy months in Odisha.
调查奥里萨邦急性发热儿童中恙虫病感染的分布和临床特征。
2017 年 6 月至 11 月期间,在 4 个农业气候区对出现急性发热(>5 天)的<15 岁儿童进行评估。对疟疾、钩端螺旋体病、登革热、伤寒和恙虫病进行了筛查。通过 IgM ELISA 和 PCR 检测确认恙虫病。
在 413 例受检者中,48.7%的患者对恙虫病呈阳性,其中 5.5%的患者出现全身并发症。17.9%的病例出现焦痂。多西环素和/或阿奇霉素 5 天的治疗对恙虫病具有临床疗效。
我们的研究表明,恙虫病是奥里萨邦雨季儿童高发病率的原因之一。