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Pak J Med Sci. 2017 Jan-Feb;33(1):177-181. doi: 10.12669/pjms.331.10847.
2
COMPARISON OF THE EFFECTS OF INTRAPLEURAL BUPIVACAINE AND MORPHINE ON POST-THORACOTOMY PAIN.胸膜内布比卡因和吗啡对开胸术后疼痛影响的比较
Middle East J Anaesthesiol. 2015 Oct;23(3):267-72.
3
Comparison of paravertebral and interpleural block in patients undergoing modified radical mastectomy.改良根治性乳房切除术患者椎旁阻滞与胸膜间阻滞的比较
J Anaesthesiol Clin Pharmacol. 2013 Oct;29(4):459-64. doi: 10.4103/0970-9185.119133.
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Negative pressure versus loss of resistance technique for interpleural block.用于胸膜间阻滞的负压与阻力消失技术
Indian J Anaesth. 2012 Mar;56(2):151-5. doi: 10.4103/0019-5049.96318.
5
Acute pain management of patients with multiple fractured ribs: a focus on regional techniques.多发性肋骨骨折患者的急性疼痛管理:关注区域技术。
Curr Opin Crit Care. 2011 Aug;17(4):323-7. doi: 10.1097/MCC.0b013e328348bf6f.
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An update on contraindications for lung function testing.肺功能测试的禁忌证更新。
Thorax. 2011 Aug;66(8):714-23. doi: 10.1136/thx.2010.139881. Epub 2010 Jul 29.
7
[Comparative study of intercostal and interpleural block for post-cholecystectomy analgesia].[肋间神经阻滞与胸膜间阻滞用于胆囊切除术后镇痛的比较研究]
Rev Bras Anestesiol. 2003 Jun;53(3):346-50.
8
Interpleural block - part 1.肋间阻滞 - 第1部分。
Anaesthesia. 2007 Oct;62(10):1039-49. doi: 10.1111/j.1365-2044.2007.05183.x.
9
Interpleural local anaesthesia: anatomical basis for mechanism of action.
Br J Anaesth. 1996 Feb;76(2):297-9. doi: 10.1093/bja/76.2.297.
10
Pro: intrapleural anesthesia is useful for thoracic analgesia.优点:胸膜内麻醉对胸部镇痛有用。
J Cardiothorac Vasc Anesth. 1996 Apr;10(3):425-8. doi: 10.1016/s1053-0770(96)80109-1.

肋间引流术后胸膜内注射佐剂进行阻滞对镇痛及肺功能影响的比较评估:一项初步研究。

Comparative evaluation of effects of intrapleural block with adjuvants on analgesia and pulmonary function after intercostal drainage: A pilot study.

作者信息

Verma R N, Sethi Navdeep, Pathak Sharmishtha, Vardhan Vasu

机构信息

Associate Professor, Department of Anaesthesiology & Critical Care, Armed Forces Medical College, Pune 411040, India.

Professor and Head, Department of Anaesthesiology & Critical Care, Armed Forces Medical College, Pune 411040, India.

出版信息

Med J Armed Forces India. 2019 Apr;75(2):164-170. doi: 10.1016/j.mjafi.2018.03.004. Epub 2018 May 28.

DOI:10.1016/j.mjafi.2018.03.004
PMID:31065185
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC6496507/
Abstract

BACKGROUND

Inter-costal chest drain (ICD) used for varied thoracic pathologies causes continuous pain and irritation of the pleura, which limits respiratory efforts and impairs ventilatory function. Intrapleural block deposits local anaesthetic between the layers of pleura and may improve ventilatory function especially in non surgical patients.

METHODS

Twenty eight ASA I-III patients treated with ICD, who could perform incentive spirometry, were included for study. They were randomized to 'Group C' (control group); 'Group B' (Bupivacaine); 'Group M' (Bupivacaine + Morphine) and 'Group D' (Bupivacaine + Dexmedetomidine). The drugs were administered via the ICD itself and clamped thereafter for 15 min. The success of the block was assessed by time for first analgesic demand, maximum inspiratory volume generated and Numerical Rating Scale score for pain; by patients.

RESULTS

Effective analgesia was observed in Group B, M and D. Addition of an adjuvant significantly prolonged time for rescue analgesic demand. Patients who received local anaesthetic alone or with an adjuvant had significantly improved maximal inspiratory volume and required lesser rescue analgesics. No significant complications were observed in any group. Pain relief in post-surgical patients using intraplural block is masked by systemic analgesics. However its application in patients with ICD for non surgical indications was explored in this study and was found to improve patient comfort and ventilation.

CONCLUSION

Intra-pleural blockade is safe and effective in relieving the constant pleural irritation and pain of ICD, thus enabling the patient to improve ventilatory effort and faster recovery of respiratory function.

摘要

背景

用于多种胸部疾病的肋间胸腔引流管(ICD)会导致持续性疼痛和胸膜刺激,这限制了呼吸努力并损害通气功能。胸膜内阻滞将局部麻醉剂注入胸膜层之间,可能改善通气功能,尤其是在非手术患者中。

方法

纳入28例接受ICD治疗、能够进行激励肺活量测定的ASA I-III级患者进行研究。他们被随机分为“C组”(对照组)、“B组”(布比卡因)、“M组”(布比卡因+吗啡)和“D组”(布比卡因+右美托咪定)。药物通过ICD本身给药,然后夹闭15分钟。通过首次镇痛需求时间、产生的最大吸气量和患者疼痛数字评分量表评分评估阻滞的成功率。

结果

在B组、M组和D组观察到有效镇痛。添加佐剂显著延长了抢救镇痛需求时间。单独接受局部麻醉剂或与佐剂一起接受局部麻醉剂的患者最大吸气量显著改善,所需抢救镇痛药较少。任何组均未观察到明显并发症。手术患者使用胸膜内阻滞的疼痛缓解被全身镇痛药掩盖。然而,本研究探讨了其在因非手术指征使用ICD的患者中的应用,发现可提高患者舒适度和通气。

结论

胸膜内阻滞在缓解ICD引起的持续性胸膜刺激和疼痛方面安全有效,从而使患者能够改善呼吸努力并更快恢复呼吸功能。