Myint Phyo Thazin, Butt Hifza Waheed, Alrifai Taha, Marin Carlos
Department of Internal Medicine, Presence Saint Joseph Hospital, Chicago, IL, USA.
Case Rep Oncol Med. 2019 Apr 1;2019:6375693. doi: 10.1155/2019/6375693. eCollection 2019.
Spontaneous tumor lysis syndrome (STLS), in the absence of prior chemo or radiation therapy, is rare with solid tumors. Here, we present a case of STLS secondary to a small-cell neuroendocrine tumor of unknown origin in a 66-year-old female patient who presented with abdominal discomfort. Computed tomography (CT) abdomen showed a large tumor mass with peritoneal metastasis, and she developed renal failure from STLS, resulting in the need for hemodialysis. Due to the progressive deterioration and the comorbidities, she opted for comfort care. Timely recognition and intervention of STLS is critical. Further studies evaluating STLS in solid tumor patients are recommended.
在没有先前化疗或放疗的情况下，实体瘤患者发生自发性肿瘤溶解综合征（STLS）的情况很少见。在此，我们报告一例66岁女性患者，因不明来源的小细胞神经内分泌肿瘤继发STLS，该患者最初表现为腹部不适。腹部计算机断层扫描（CT）显示有一个伴有腹膜转移的大肿瘤块，她因STLS发展为肾衰竭，需要进行血液透析。由于病情逐渐恶化以及合并症，她选择了姑息治疗。及时识别和干预STLS至关重要。建议进一步开展针对实体瘤患者STLS的研究。
