银屑病中存在非特异性淋巴细胞反应性降低。
Depressed non-specific lymphocyte reactivity in psoriasis.
作者信息
Lindholm L, Magnusson B L, Mobacken H
出版信息
Arch Dermatol Res. 1978 Nov 10;263(2):121-5. doi: 10.1007/BF00446432.
PMID:310658
Abstract
T-lymphocyte number and functions were studied in 24 patients with psoriasis guttata as compared to healthy controls. A decrease was found of the in vitro ability to synthetize DNA in response to stimulation with phytohemagglutinin (PHA), concanavalin A, poke weed mitogen and PPD, which was statistically significant for PHA. The percentage and absolute numbers of both T and B peripheral blood lymphocytes were not altered.
摘要
对24例点滴状银屑病患者的T淋巴细胞数量和功能进行了研究，并与健康对照者进行比较。发现其对植物血凝素（PHA）、刀豆球蛋白A、商陆有丝分裂原和结核菌素纯蛋白衍生物刺激的体外DNA合成能力下降，其中PHA刺激下的下降具有统计学意义。外周血T淋巴细胞和B淋巴细胞的百分比及绝对数量均未改变。
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