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重度抑郁症中的淋巴细胞功能

Lymphocyte function in major depressive disorder.

作者信息

Schleifer S J, Keller S E, Meyerson A T, Raskin M J, Davis K L, Stein M

出版信息

Arch Gen Psychiatry. 1984 May;41(5):484-6. doi: 10.1001/archpsyc.1984.01790160070008.

DOI:10.1001/archpsyc.1984.01790160070008
PMID:6609689
Abstract

Lymphocyte stimulation by phytohemagglutinin, concanavalin A, and pokeweed mitogen was significantly lower in a group of hospitalized depressed patients than in matched controls. The absolute number of T and B cells was lower in the depressed group, but the percentage of these cell types did not differ between the groups. These findings may be related to the altered neuroendocrine function found in patients with depressive disorders.

摘要

在一组住院抑郁症患者中,植物血凝素、刀豆球蛋白A和商陆有丝分裂原对淋巴细胞的刺激作用明显低于匹配的对照组。抑郁症组中T细胞和B细胞的绝对数量较低,但这些细胞类型的百分比在两组之间没有差异。这些发现可能与抑郁症患者神经内分泌功能改变有关。

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