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外翻式和补片式颈动脉内膜切除术的早期血流动力学特征。

Early hemodynamic characteristics of eversion and patch carotid endarterectomies.

作者信息

Chait Jesse, Nicoara Michael, Kibrik Pavel, Ostrozhynskyy Yuriy, Marks Natalie, Rajaee Sareh, Hingorani Anil, Ascher Enrico

机构信息

Division of Vascular Surgery, NYU Langone Hospital-Brooklyn, Brooklyn, NY, USA.

出版信息

J Ultrasound. 2019 Dec;22(4):433-436. doi: 10.1007/s40477-019-00384-3. Epub 2019 May 8.

Abstract

OBJECTIVE

Carotid endarterectomy (CEA) is currently the gold standard in the operative management of carotid artery stenosis. While eversion and patch CEAs vary greatly in technique, various studies have determined equivalence with regard to clinical outcomes. However, the hemodynamic differences following each procedure are not known. This study aimed to investigate any early hemodynamic differences between eversion and patch CEAs.

METHODS

All CEAs performed at our institution from March 2012 to June 2018 were aggregated in a retrospective database by querying the 35301 CPT code from the electronic medical record system. Variables collected included gender, age, laterality of CEA, type of procedure, and pre- and post-operative duplex ultrasound (DUS) date and quantitative findings. Exclusion criteria included any procedure with incomplete data, a post-operative DUS > 90 days following the procedure, CEAs with concomitant bypass(es), isolated external carotid artery (ECA) endarterectomies, and re-do CEAs.

RESULTS

One hundred and seventy-one CEAs were performed in 161 unique patients. There were 101 males and 60 females, with an average age of 69.7 (38-96; ± 9.36). 63 CEAs were excluded from analysis: 51 due to incomplete data, eight with a > 90 day post-operative DUS, 2 isolated ECA endarterectomies, 1 CEA with a carotid-subclavian bypass, and 1 re-do CEA secondary to an infected patch. Twenty-seven eversion and 81 patch CEAs were included in analysis. There was no difference in procedure laterality or gender between the two cohorts (p > 0.05); however, patients who received an eversion CEA were older on average (73.3 vs 67.5; p = 0.002). Pre-operative peak systolic velocities (PSV) of the proximal internal carotid artery (ICA), distal ICA, and distal common artery (CCA) were all similar (p > 0.05). Post-operative DUS was performed at 17.0 and 12.9 days in the eversion and patch CEA cohorts, respectively (p = 0.12). Post-operative PSV and change in PSV were similar for all three aforementioned segments (p > 0.05).

CONCLUSION

Although eversion and patch CEAs vary greatly in technique and post-procedure anatomy, there was no significant difference in post-operative PSV or change in PSV at or around the carotid bifurcation.

摘要

目的

颈动脉内膜切除术(CEA)是目前颈动脉狭窄手术治疗的金标准。虽然外翻式和补片式CEA在技术上有很大差异,但多项研究已确定它们在临床结果方面具有等效性。然而,每种手术术后的血流动力学差异尚不清楚。本研究旨在调查外翻式和补片式CEA之间早期的血流动力学差异。

方法

通过查询电子病历系统中的35301 CPT代码,将2012年3月至2018年6月在我院进行的所有CEA汇总到一个回顾性数据库中。收集的变量包括性别、年龄、CEA的侧别、手术类型以及术前和术后双功超声(DUS)检查日期和定量结果。排除标准包括数据不完整的任何手术、术后DUS检查时间超过术后90天的手术、伴有旁路手术的CEA、单纯颈外动脉(ECA)内膜切除术以及再次进行的CEA。

结果

161例独特患者共进行了171例CEA。其中男性101例,女性60例,平均年龄69.7岁(38 - 96岁;±9.36)。63例CEA被排除在分析之外:51例因数据不完整,8例术后DUS检查时间超过90天,2例单纯ECA内膜切除术,1例伴有颈动脉 - 锁骨下动脉旁路手术的CEA,以及1例因补片感染而再次进行的CEA。27例外翻式和81例补片式CEA纳入分析。两组在手术侧别或性别方面无差异(p>0.05);然而,接受外翻式CEA的患者平均年龄更大(73.3岁对67.5岁;p = 0.002)。颈内动脉(ICA)近端、ICA远端和颈总动脉(CCA)远端术前的收缩期峰值流速(PSV)均相似(p>0.05)。外翻式和补片式CEA组术后DUS检查分别在术后17.0天和12.9天进行(p = 0.12)。上述三个节段术后的PSV及PSV变化相似(p>0.05)。

结论

虽然外翻式和补片式CEA在技术和术后解剖结构上有很大差异,但在颈动脉分叉处或其周围,术后PSV或PSV变化无显著差异。

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