Sumarokov D D
Vopr Med Khim. 1987 Jan-Feb;33(1):51-4.
Rat bones demineralized in HCl and TCA exhibited distinct osteoinductive activity while the bones demineralized using EDTA did not show the activity. HCl- and TCA-extracts of bones differed from EDTA extracts by chromatographic and radiochromatographic profiles. At the same time, HCl- and TCA-extracts contained additional fraction. The substances involved in the fraction appear to be responsible for inhibition of the osteoinductive factor of bone tissue.
在盐酸（HCl）和三氯乙酸（TCA）中脱矿质的大鼠骨骼表现出明显的骨诱导活性，而使用乙二胺四乙酸（EDTA）脱矿质的骨骼则未显示出该活性。骨骼的HCl提取物和TCA提取物在色谱和放射色谱图谱上与EDTA提取物不同。同时，HCl提取物和TCA提取物含有额外的组分。该组分中涉及的物质似乎是抑制骨组织骨诱导因子的原因。
