[酸性代谢产物对骨基质骨诱导活性的影响]
[Effect of acid metabolites on the osteoinductive activity of the bone matrix].
作者信息
Sumarokov D D, Shamsudinov A Kh, Shvyrkov M B, Siziakov S L
出版信息
Nauchnye Doki Vyss Shkoly Biol Nauki. 1987(5):20-4.
PMID:3300788
Abstract
The osteoinductive activity of bone matrix demineralized in acid metabolites of glycolysis and Krebs cycle have been studied in rats. The highest osteoinductive effect was reached during the demineralization in oxaloacetic acid, the lowest one--in the malic acid. The regulatory role of glycolysis metabolites and Krebs Cycle in posttraumatic osteogenesis is under discussion.
摘要
在大鼠中研究了在糖酵解和三羧酸循环的酸性代谢产物中脱矿质的骨基质的骨诱导活性。在草酰乙酸中脱矿质时达到最高的骨诱导效果，在苹果酸中脱矿质时效果最低。正在讨论糖酵解代谢产物和三羧酸循环在创伤后骨生成中的调节作用。
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