Xiang Sishi, Li Guilin, He Chuan, Ren Jian, Zhang Hongqi
Department of Neurosurgery, Xuanwu Hospital, Capital Medical University, Beijing, China.
Interv Neuroradiol. 2019 Oct;25(5):548-555. doi: 10.1177/1591019918824413. Epub 2019 May 9.
Preliminary studies suggest that Willis covered stents may be suitable for the treatment of aneurysms of the internal carotid artery (ICA), but their efficacy and safety in vertebral artery (VA) dissecting aneurysms need further investigation.
Consecutive patients who underwent placement of a Willis covered stent for treatment of an aneurysm of the V4 segment of the VA between September 2015 and December 2017 at our institution were retrospectively reviewed. The efficacy, complications, angiographic and clinical follow-up results were collected and analyzed.
Sixteen covered stents were successfully implanted into the VA in 12 patients with 12 dissecting aneurysms. The technical success rate of stenting placement was 100%. Complete occlusion was achieved in 11 patients immediately after stent placement, with transient endoleak in one aneurysm. Angiographic follow-up (9.9 ± 4.0 months, mean±SD) was performed in nine patients and demonstrated complete stabilization of the obliterated aneurysm. Clinical follow-up (20.1 ± 9.6 months, mean±SD) demonstrated full recovery in 11 patients, and one patient suffered from acute myocardial infarction.
Reconstruction using a Willis covered stent is an efficient, safe and attractive alternative for the definitive treatment of intracranial VA dissecting aneurysms; longer follow-up and expanded clinical trials are needed for further validation of this technique.
初步研究表明,Willis覆膜支架可能适用于治疗颈内动脉(ICA)动脉瘤,但其在椎动脉(VA)夹层动脉瘤治疗中的有效性和安全性尚需进一步研究。
回顾性分析2015年9月至2017年12月在我院接受Willis覆膜支架置入术治疗VA V4段动脉瘤的连续患者。收集并分析其疗效、并发症、血管造影及临床随访结果。
12例患有12个夹层动脉瘤的患者成功地在VA中植入了16个覆膜支架。支架置入的技术成功率为100%。11例患者在支架置入后立即实现完全闭塞,1个动脉瘤出现短暂内漏。对9例患者进行了血管造影随访(平均±标准差,9.9±4.0个月),结果显示闭塞的动脉瘤完全稳定。临床随访(平均±标准差,20.1±9.6个月)显示11例患者完全康复,1例患者发生急性心肌梗死。
使用Willis覆膜支架进行重建是颅内VA夹层动脉瘤确定性治疗的一种有效、安全且有吸引力的替代方法;需要更长时间的随访和扩大临床试验以进一步验证该技术。