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采用 Willis 覆膜支架血管内治疗颈动脉虹吸段动脉瘤的单中心经验:回顾性分析。

A single-center experience in the endovascular treatment of carotid siphon aneurysms using the Willis covered stent: a retrospective analysis.

机构信息

Department of Interventional Radiology, Shanghai Tongji Hospital, Tongji University School of Medicine, Shanghai, China.

出版信息

J Neurointerv Surg. 2018 Dec;10(12):1197-1202. doi: 10.1136/neurintsurg-2017-013695. Epub 2018 Apr 21.

Abstract

OBJECTIVE

To report the clinical results and initial clinical experience of endovascular isolation with the Willis covered stent for carotid siphon aneurysms.

METHODS

Between November 2013 and December 2016, a total of 57 patients who presented with carotid siphon aneurysms were treated with the Willis covered stent. Results of the procedures, technical events, and complications were recorded. Clinical and imaging follow-ups were performed at 3 months following the endovascular procedures.

RESULTS

Placement of the Willis covered stent was successful in all patients. Immediate angiography revealed complete exclusion of aneurysms in 48 patients (84%), while endoleak occurred in nine patients (16%). Procedure-related complications occurred in three cases, including displacement of the covered stent in one patient, acute in-stent thrombosis in one patient, and microwire-related intracranial hemorrhage in one patient. Angiographic follow-ups were done in 49 patients, with complete exclusion of aneurysms in 47 patients. Endoleak was present in two patients. No aneurysm recurrence occurred. Forty-four patients showed good parent artery patency, while the other five patients showed mild to moderate asymptomatic in-stent stenosis. During the follow-up period, no ischemic or hemorrhagic event occurred. The modified Rankin Scale scores at follow-up were 0-2 in 56 patients and >2 in one patient.

CONCLUSIONS

The treatment of siphon aneurysms with Willis covered stent implantation resulted in satisfactory clinical outcomes. The Willis covered stent seems safe and feasible for the treatment of siphon aneurysms, which still needs to be confirmed by longer follow-up periods and controlled studies with larger samples.

摘要

目的

报告 Willis 覆膜支架血管内隔离治疗颈内动脉虹吸段动脉瘤的临床结果和初步经验。

方法

2013 年 11 月至 2016 年 12 月,共 57 例颈内动脉虹吸段动脉瘤患者接受 Willis 覆膜支架治疗。记录手术结果、技术事件和并发症。在血管内手术后 3 个月进行临床和影像学随访。

结果

所有患者均成功放置 Willis 覆膜支架。即刻血管造影显示 48 例(84%)患者动脉瘤完全闭塞,9 例(16%)发生内漏。3 例发生与手术相关的并发症,包括 1 例覆膜支架移位,1 例急性支架内血栓形成,1 例微导丝相关颅内出血。49 例患者进行了血管造影随访,47 例患者动脉瘤完全闭塞,2 例患者存在内漏。无动脉瘤复发。44 例患者的载瘤动脉通畅良好,5 例患者存在轻度至中度无症状支架内狭窄。随访期间无缺血或出血事件发生。56 例患者改良 Rankin 量表评分为 0-2 分,1 例患者评分为>2 分。

结论

Willis 覆膜支架植入治疗虹吸段动脉瘤的临床效果满意。Willis 覆膜支架治疗虹吸段动脉瘤安全可行,但仍需要通过更长的随访期和更大样本的对照研究来进一步证实。

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