海洋来源的链霉菌属菌株F001的基因组序列，阿卡辛A和二氮喹诺霉素的产生菌
Genome Sequence of Marine-Derived sp. Strain F001, a Producer of Akashin A and Diazaquinomycins.
作者信息
Braesel Jana, Clark Chase M, Kunstman Kevin J, Green Stefan J, Maienschein-Cline Mark, Murphy Brian T, Eustáquio Alessandra S
机构信息
Department of Medicinal Chemistry and Pharmacognosy and Center for Biomolecular Sciences, College of Pharmacy, University of Illinois at Chicago, Chicago, Illinois, USA.
Sequencing Core, University of Illinois at Chicago, Chicago, Illinois, USA.
出版信息
Microbiol Resour Announc. 2019 May 9;8(19):e00165-19. doi: 10.1128/MRA.00165-19.
Abstract
We report the 9.7-Mb genome sequence of sp. strain F001, isolated from a marine sediment sample from Raja Ampat, Indonesia. F001 produces diazaquinomycins, which exhibit potent and selective antituberculosis activity. In addition, it is also known to produce akashin A, a blue pigment that has shown cytotoxic activity.
摘要
我们报告了从印度尼西亚拉贾安帕特的海洋沉积物样本中分离出的**sp.**菌株F001的9.7兆碱基基因组序列。F001产生二氮杂喹霉素，其具有强大的选择性抗结核活性。此外，已知它还能产生阿卡辛A，一种具有细胞毒性活性的蓝色色素。
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