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进行小儿脑死亡检查及脑死亡宣告

Performing the Brain Death Examination and the Declaration of Pediatric Brain Death.

作者信息

Martin Susan D, Porter Melissa B

机构信息

Division of Pediatric Critical Care, Department of Pediatrics, University of Louisville School of Medicine, Louisville, Kentucky, United States.

出版信息

J Pediatr Intensive Care. 2017 Dec;6(4):229-233. doi: 10.1055/s-0037-1604013. Epub 2017 Jun 27.

DOI:10.1055/s-0037-1604013
PMID:31073455
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC6260313/
Abstract

Declaration of brain death is a clinical diagnosis made by the absence of neurological function in a comatose patient secondary to a known irreversible cause. Brain death determination is not an infrequent process in pediatric intensive care units. It is important that pediatric intensive care providers understand the definition of brain death and intensivists are able to implement brain death testing. The following is a narration detailing the process of brain death determination by physical examination. First, the prerequisites that determine patients' eligibility for brain death testing will be outlined. Next, each part of the physical exam, including the apnea test, will be described in detail. Finally, how the declaration of brain death is made is stated. In addition, special considerations and ancillary testing will be briefly highlighted.

摘要

脑死亡的判定是对因已知不可逆病因导致昏迷的患者,基于其神经功能缺失所做出的临床诊断。在儿科重症监护病房,脑死亡判定并非罕见的过程。儿科重症监护医护人员理解脑死亡的定义且重症医学专家能够实施脑死亡检测非常重要。以下是详细叙述通过体格检查判定脑死亡的过程。首先,将概述确定患者是否适合进行脑死亡检测的先决条件。接下来,将详细描述体格检查的每个部分,包括呼吸暂停试验。最后,说明如何做出脑死亡判定。此外,还将简要强调特殊注意事项和辅助检查。

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本文引用的文献

1
Apnea test during brain death assessment in mechanically ventilated and ECMO patients.机械通气和 ECMO 患者脑死亡评估中的呼吸暂停试验。
Intensive Care Med. 2016 Jan;42(1):72-81. doi: 10.1007/s00134-015-4105-6. Epub 2015 Nov 10.
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Apnea test in the determination of brain death in patients treated with extracorporeal membrane oxygenation (ECMO).体外膜肺氧合(ECMO)治疗患者脑死亡判定中的 apnea 试验 。 注:这里“apnea test”常见释义为“ apnea试验”,但“apnea”准确意思是“呼吸暂停” ,具体准确理解需结合医学背景知识进一步明确其在该语境下的含义。
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Factors Affecting the Occurrence of Spinal Reflexes in Brain Dead Cases.影响脑死亡病例中脊髓反射发生的因素。
Exp Clin Transplant. 2015 Aug;13(4):309-12.
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Apnea testing on extracorporeal membrane oxygenation: Case report and literature review.体外膜肺氧合的呼吸暂停试验:病例报告及文献综述
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Pediatric brain death determination.小儿脑死亡判定
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Performance of an apnea test for brain death determination in a patient receiving venoarterial extracorporeal membrane oxygenation.在接受静脉-动脉体外膜肺氧合治疗的患者中进行用于判定脑死亡的 apnea 试验的情况。 (注:这里“apnea test”常见的准确说法是“ apnea test”,直译为“呼吸暂停试验”,但在医学语境中一般称为“ apnea试验” ,具体翻译可根据实际医学术语习惯调整 )
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Epidemiology of death in the PICU at five U.S. teaching hospitals*.美国五家教学医院儿科重症监护病房的死亡流行病学*
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Brain death: assessment, controversy, and confounding factors.
Crit Care Nurse. 2013 Dec;33(6):27-46. doi: 10.4037/ccn2013215.
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Developing a standard method for apnea testing in the determination of brain death for patients on venoarterial extracorporeal membrane oxygenation: a pediatric case series.在使用体外膜肺氧合(VA-ECMO)治疗的患者中,开发一种用于确定脑死亡的呼吸暂停测试的标准方法:一项儿科病例系列研究。
Pediatr Crit Care Med. 2014 Feb;15(2):e38-43. doi: 10.1097/PCC.0000000000000006.
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Apnea test for brain death determination in a patient on extracorporeal membrane oxygenation.体外膜肺氧合患者脑死亡判定的呼吸暂停试验。
Neurocrit Care. 2013 Oct;19(2):215-7. doi: 10.1007/s12028-013-9845-y.