Leiman B C, Katz J, Stanley T H, Butler B D
Anesth Analg. 1987 Jun;66(6):529-32.
Artificial secretions were removed by suction (using 12- or 18-French suction catheters) or by means of a balloon-tipped catheter (6-French Fogarty arterial embolectomy catheter) in 20 experiments performed on five dogs anesthetized with halothane. Each dog had 5 ml of mucin injected 10 cm down the endotracheal tube prior to a 30-sec period of intermittent positive pressure ventilation. After this procedure, the ventilator was disconnected and the secretions were removed by suction with the 12- or 18-French catheters or by the Fogarty catheter. Each dog had balloon removal performed twice and suction performed once with the 12-French and once with the 18-French catheter. The endotracheal tube was cleaned and a 15-min stabilization period was allowed between each experiment. Arterial blood pressure (MAP) and pulmonary artery pressure (PAP) did not change after either technique. There were no ECG changes, arrhythmias, or alterations in PaCO2. The PaO2 was significantly lower in the two suction catheter groups [520 +/- 33 mm Hg (12 French) and 451 +/- 31 mm Hg (18 French)] than in the balloon removal group (564 +/- 10 mm Hg) (P less than 0.05). The balloon technique removed more secretions (4.52 +/- 0.06 ml) than did suction (12 French, 1.32 +/- 0.17 ml; 18 French, 2.11 +/- 0.44 ml). Balloon removal of tracheal secretions has two advantages over conventional suction techniques: it removes more secretions, and it has less detrimental effect on arterial oxygenation.
在对五只用氟烷麻醉的狗进行的20次实验中，通过抽吸（使用12或18法式抽吸导管）或借助带球囊导管（6法式Fogarty动脉栓子切除术导管）清除人工分泌物。在进行30秒的间歇性正压通气之前，每只狗在气管内导管向下10厘米处注入5毫升粘蛋白。此操作后，断开呼吸机，并用12或18法式导管抽吸或用Fogarty导管清除分泌物。每只狗进行两次球囊清除，用12法式导管抽吸一次，用18法式导管抽吸一次。清洁气管内导管，每次实验之间留出15分钟的稳定期。两种技术操作后，动脉血压（MAP）和肺动脉压（PAP）均未改变。未出现心电图变化、心律失常或PaCO2改变。两个抽吸导管组的PaO2显著低于球囊清除组[520±33毫米汞柱（12法式）和451±31毫米汞柱（18法式）对比564±10毫米汞柱]（P<0.05）。球囊技术清除的分泌物（4.52±0.06毫升）比抽吸技术多（12法式，1.32±0.17毫升；18法式，2.11±0.44毫升）。与传统抽吸技术相比，球囊清除气管分泌物有两个优点：清除的分泌物更多，对动脉氧合的不利影响更小。
