来自. 绿色核桃壳的新二氢四氢异喹啉葡萄糖苷。
New -ditetralonyl glucoside from the green walnut husk of .
机构信息
School of Traditional Chinese Medicine, Shenyang Pharmaceutical University, Shenyang, China.
Key Laboratory of Structure-Based Drug Design & Discovery, Ministry of Education, Shenyang Pharmaceutical University, Shenyang, China.
出版信息
Nat Prod Res. 2020 Nov;34(21):3066-3072. doi: 10.1080/14786419.2019.1608538. Epub 2019 May 10.
One new -ditetralonyl glucoside (, was isolated from the green walnut husk of (Juglandaceae), together with twelve known compounds (). The structure of the new compound was determined as (2,4,10,12)-2-[7-(12,13,16-trihydroxy--tetralonyl-13---D-glucopyranoside)]- 4,8-dihydroxy--tetralone-4---D-glucopyranoside (), on the basis of detailed spectroscopic analyses, and acidic hydrolysis. Compounds , and were isolated from the genus for the first time. Compound showed weak cytotoxic against A549 and HeLa cell lines.
从胡桃科（Juglandaceae）绿核桃壳中分离得到一种新的二氢查尔酮葡萄糖苷（），此外还分离得到 12 种已知化合物（）。基于详细的光谱分析和酸性水解，确定新化合物的结构为（2,4,10,12）-2-[7-（12,13,16-三羟基-4,8-二氢-二氢查尔酮-13--D-吡喃葡萄糖苷）]-4,8-二羟基-二氢查尔酮-4---D-吡喃葡萄糖苷（）。化合物、和从属中首次分离得到。化合物对 A549 和 HeLa 细胞系表现出微弱的细胞毒性。
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