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生长受限胎儿的产前窒息、高乳酸血症、低血糖症和胎儿成红细胞增多症。

Prenatal asphyxia, hyperlacticaemia, hypoglycaemia, and erythroblastosis in growth retarded fetuses.

作者信息

Soothill P W, Nicolaides K H, Campbell S

出版信息

Br Med J (Clin Res Ed). 1987 Apr 25;294(6579):1051-3. doi: 10.1136/bmj.294.6579.1051.

DOI:10.1136/bmj.294.6579.1051
PMID:3107690
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC1246217/
Abstract

The umbilical venous oxygen and carbon dioxide tensions, pH, lactate and glucose concentrations, nucleated red cell (erythroblast) count, and haemoglobin concentration were measured in 38 cases of intrauterine growth retardation in which fetal blood sampling was performed by cordocentesis. The oxygen tension was below the normal mean for gestational age in 33 cases; in 14 it was below the lower limit of the 95% confidence interval for normal pregnancies. The severity of fetal hypoxia correlated significantly with fetal hypercapnia, acidosis, hyperlacticaemia, hypoglycaemia, and erythroblastosis. These findings indicate that "birth asphyxia" is not necessarily due to the process of birth.

摘要

对38例宫内生长迟缓病例进行了脐静脉氧分压、二氧化碳分压、pH值、乳酸和葡萄糖浓度、有核红细胞(成红细胞)计数及血红蛋白浓度的测定,这些病例均通过脐静脉穿刺术采集胎儿血样。33例病例的氧分压低于胎龄正常均值;14例低于正常妊娠95%置信区间的下限。胎儿缺氧的严重程度与胎儿高碳酸血症、酸中毒、高乳酸血症、低血糖症和成红细胞增多症显著相关。这些发现表明,“出生窒息”不一定是由出生过程导致的。

相似文献

1
Prenatal asphyxia, hyperlacticaemia, hypoglycaemia, and erythroblastosis in growth retarded fetuses.生长受限胎儿的产前窒息、高乳酸血症、低血糖症和胎儿成红细胞增多症。
Br Med J (Clin Res Ed). 1987 Apr 25;294(6579):1051-3. doi: 10.1136/bmj.294.6579.1051.
2
Utero-placental blood velocity resistance index and umbilical venous pO2, pCO2, pH, lactate and erythroblast count in growth-retarded fetuses.生长受限胎儿的子宫胎盘血流速度阻力指数及脐静脉血氧分压、二氧化碳分压、pH值、乳酸和有核红细胞计数
Fetal Ther. 1986;1(4):176-9. doi: 10.1159/000262265.
3
[Biochemical profile of fetal blood sampled by cordocentesis in 35 pregnancies complicated by growth retardation].[35例合并胎儿生长受限妊娠经脐静脉穿刺采集胎儿血的生化指标分析]
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Relation of fetal hypoxia in growth retardation to mean blood velocity in the fetal aorta.生长受限胎儿缺氧与胎儿主动脉平均血流速度的关系。
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Plasma adenosine concentration in appropriate- and small-for-gestational-age fetuses.适于胎龄和小于胎龄胎儿的血浆腺苷浓度
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8
The value of fetal arterial, cardiac and venous flows in predicting pH and blood gases measured in umbilical blood at cordocentesis in growth retarded fetuses.胎儿动脉、心脏和静脉血流在预测生长受限胎儿脐血穿刺时脐血中测量的pH值和血气方面的价值。
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The impact of gestational age and fetal growth on the maternal-fetal glucose concentration difference.孕周和胎儿生长对母胎血糖浓度差异的影响。
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Acid-base characteristics of fetuses with intrauterine growth retardation during labor and delivery.分娩过程中宫内生长受限胎儿的酸碱特征。
Am J Obstet Gynecol. 1980 Jul 1;137(5):553-9. doi: 10.1016/0002-9378(80)90695-x.

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本文引用的文献

1
Perinatal morbidity and mortality in small-for-dates babies: the relative importance of some maternal factors.小于胎龄儿的围产期发病率和死亡率:某些母体因素的相对重要性。
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Problems of the small-for-dates baby.小于胎龄儿的问题。
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Polycythemia in small for gestational age infants.小于胎龄儿的红细胞增多症
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Neonatal hypoglycaemia.新生儿低血糖症
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Increased gluconeogenic substrates in the small-for-gestational-age infant.小于胎龄儿体内糖异生底物增加。
N Engl J Med. 1974 Aug 15;291(7):322-8. doi: 10.1056/NEJM197408152910702.
6
Relationship of fetal hemoglobin and oxygen content to lactate concentration in Rh isoimmunized pregnancies.Rh血型同种免疫妊娠中胎儿血红蛋白、氧含量与乳酸浓度的关系。
Obstet Gynecol. 1987 Feb;69(2):268-71.
7
Ultrasound-guided sampling of umbilical cord and placental blood to assess fetal wellbeing.超声引导下采集脐带血和胎盘血以评估胎儿健康状况。
Lancet. 1986 May 10;1(8489):1065-7. doi: 10.1016/s0140-6736(86)91333-4.
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Rapid karyotyping in non-lethal fetal malformations.
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9
Hyperfibrinogenemia and polycythemia with intrauterine growth retardation in fetal lambs.胎羊高纤维蛋白原血症、红细胞增多症与宫内生长迟缓
Am J Obstet Gynecol. 1976 Feb 1;124(3):268-71. doi: 10.1016/0002-9378(76)90155-1.
10
Ultrasonic measurement of fetal abdomen circumference in the estimation of fetal weight.超声测量胎儿腹围以估计胎儿体重。
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