Pulmonary and Critical Care Medicine, University of Alabama at Birmingham, Birmingham, Alabama, USA.
Department of Epidemiology and Biostatistics, Drexel University, Philadelphia, Pennsylvania, USA.
BMJ Open. 2019 May 10;9(5):e027175. doi: 10.1136/bmjopen-2018-027175.
While awareness of cigarette smoking's harmful effects has increased, determinants associated with smoking status remain understudied, including potential racial differences. We aim to examine factors associated with former versus current smoking status and assess whether these associations differed by race.
We performed a cross-sectional analysis using the population-based Reasons for Geographic and Racial Differences in Stroke(REGARDS)study.
Logistic regression was used to calculate the OR of former smoking status compared with current smoking status with risk factors of interest. Race interactions were tested using multiplicative interaction terms.
16 463 participants reported smoking at least 100 cigarettes in their lifetime. Seventy-three per cent (n=12 067) self-reported former-smoker status. Physical activity (reference (REF) <3×/week; >3×/week: OR=1.26, 95% CI 1.11 to 1.43), adherence to Mediterranean diet (REF: low; medium: OR=1.46, 95% CI 1.27 to 1.67; high: OR=2.20, 95% CI 1.84 to 2.64), daily television viewing time (REF: >4 hours; <1 hour: OR=1.32, 95% CI 1.10 to 1.60) and abstinence from alcohol use (REF: heavy; none: OR=1.50, 95% CI 1.18 to 1.91) were associated with former-smoker status. Male sex, higher education and income $35 000-$74 000 (REF: <$20 000) were also associated with former-smoker status. Factors associated with lower odds of reporting former-smoker status were younger age (REF: ≥65 years; 45-64 years: OR=0.34, 95% CI 0.29 to 0.39), black race (OR=0.62, 95% CI 0.53 to 0.72) and single marital status (REF: married status; OR=0.66, 95% CI 0.51 to 0.87), being divorced (OR=0.60, 95% CI 0.50 to 0.72) or widowed (OR=0.70, 95% CI 0.57 to 0.85). Significant interactions were observed between race and alcohol use and dyslipidaemia, such that black participants had higher odds of reporting former-smoker status if they were abstinent from alcohol (OR=2.32, 95% CI 1.47 to 3.68) or had a history of dyslipidaemia (OR=1.31, 95% CI 1.06 to 1.62), whereas these relationships were not statistically significant in white participants.
Efforts to promote tobacco cessation should consist of targeted behavioural interventions that incorporate racial differences.
尽管人们对吸烟有害的认识有所提高,但与吸烟状况相关的决定因素仍研究不足,包括潜在的种族差异。我们旨在研究与既往吸烟状态与当前吸烟状态相关的因素,并评估这些关联是否因种族而异。
我们使用基于人群的地理和种族差异中风原因研究(REGARDS)进行了一项横断面分析。
使用逻辑回归计算与感兴趣的危险因素相比,既往吸烟状态的比值比(OR)。使用乘法交互项检验种族间的相互作用。
16463 名参与者报告至少吸过 100 支香烟。73%(n=12067)自我报告为既往吸烟者。体力活动(参考(REF)<3/周;>3/周:OR=1.26,95%CI 1.11 至 1.43)、遵循地中海饮食(REF:低;中:OR=1.46,95%CI 1.27 至 1.67;高:OR=2.20,95%CI 1.84 至 2.64)、每天看电视时间(REF:>4 小时;<1 小时:OR=1.32,95%CI 1.10 至 1.60)和戒酒(REF:重度;无:OR=1.50,95%CI 1.18 至 1.91)与既往吸烟者状态相关。男性、较高的教育程度和收入在 35000 美元至 74000 美元之间(REF:<20000 美元)也与既往吸烟者状态相关。与报告既往吸烟者状态的可能性较低相关的因素包括年龄较小(REF:≥65 岁;45-64 岁:OR=0.34,95%CI 0.29 至 0.39)、黑种人(OR=0.62,95%CI 0.53 至 0.72)和单身婚姻状况(REF:已婚状况;OR=0.66,95%CI 0.51 至 0.87)、离婚(OR=0.60,95%CI 0.50 至 0.72)或丧偶(OR=0.70,95%CI 0.57 至 0.85)。在种族和饮酒与血脂异常之间观察到显著的相互作用,即黑人参与者如果戒酒(OR=2.32,95%CI 1.47 至 3.68)或有血脂异常史(OR=1.31,95%CI 1.06 至 1.62),他们报告既往吸烟者状态的可能性更高,而这些关系在白人参与者中并不具有统计学意义。
促进戒烟的努力应包括针对具有种族差异的目标性行为干预措施。