Olivatto Gabriela Marsola, Teixeira Carla Regina de Souza, Sisdelli Marcela Ganzella, Zanetti Maria Lúcia, Silveira Renata Cristina de Campos Pereira, Gonçalves Claudio Vinicius
Escola de Enfermagem de Ribeirão Preto da Universidade de São Paulo (EERP-USP), Ribeirão Preto, SP, Brazil.
Escola de Enfermagem de Ribeirão Preto da Universidade de São Paulo (EERP-USP), Ribeirão Preto, SP, Brazil.
Hematol Transfus Cell Ther. 2019 Apr-Jun;41(2):139-144. doi: 10.1016/j.htct.2018.08.005. Epub 2018 Dec 31.
This is a quantitative transversal study that aimed to analyze the sociodemographic and clinical characteristics of thalassemia major patients with and without diabetes mellitus.
The cohort consisted of 31 thalassemia major patients from a reference center of treatment in Brazil in 2016. The data were obtained from an interview using a questionnaire containing demographic and clinical variables. The results show that 16.1% of the participants with thalassemia major had diabetes mellitus. The participants' ages ranged from 20 to 48 years, with an average of 35 years, mostly students and starting in the formal job market. The most commonly used treatment was the oral desferasirox and the transfusion treatment interval was 15-22 days.
Patients with thalassemia major and diabetes mellitus presented altered values of fasting glycemia, serum alanine transaminase, magnetic resonance imaging and bone densitometry.
It was concluded that knowledge of the characteristics of this population contributes in the proposal of effective educational strategies in light of the complexity of care and the progression of the disease.
这是一项定量横断面研究，旨在分析患有和未患有糖尿病的重型地中海贫血患者的社会人口学和临床特征。
该队列由2016年来自巴西一个治疗参考中心的31例重型地中海贫血患者组成。数据通过使用包含人口统计学和临床变量的问卷进行访谈获得。结果显示，16.1%的重型地中海贫血参与者患有糖尿病。参与者年龄在20至48岁之间，平均35岁，大多数是学生且刚开始进入正规就业市场。最常用的治疗方法是口服地拉罗司，输血治疗间隔为15 - 22天。
患有重型地中海贫血和糖尿病的患者空腹血糖、血清丙氨酸转氨酶、磁共振成像和骨密度测定值出现改变。
得出的结论是，鉴于护理的复杂性和疾病的进展，了解该人群的特征有助于提出有效的教育策略。
