Mayerson Center for Safe and Healthy Children, Cincinnati Children's Hospital Medical Center, Cincinnati, OH.
Division of Biostatistics and Epidemiology, Cincinnati Children's Hospital Medical Center, Cincinnati, OH; Department of Pediatrics, University of Cincinnati College of Medicine, Cincinnati, OH.
J Pediatr. 2019 Aug;211:146-151. doi: 10.1016/j.jpeds.2019.04.025. Epub 2019 May 10.
To determine whether maternal and paternal exposure to adverse childhood experiences (ACEs) has an association with offspring healthcare use by 2 years of age.
A retrospective cohort study was performed on 454 patients at a large suburban pediatric primary care practice whose mother (n = 374) or father (n = 156) or both (n = 123) completed an ACE survey between October 2012 and June 2014. The association between self-reported parental ACEs and healthcare use by 2 years of age, including number of missed well-child visits, sick visits, and delayed or missed immunizations, was modeled using multivariable negative binomial regression. All analyses adjusted for child sex, payer source, and preterm birth.
Maternal, but not paternal, ACE exposure was significantly associated with missed well-child visits by 2 years of age. For each additional maternal ACE, there was a significant 12% increase in the incidence rate of missed well-child visits (relative risk, 1.12; 95% CI, 1.03-1.22; P = .010). Maternal and paternal ACE scores were not significantly associated with increased sick visits or delayed or missed immunizations.
The ACE exposure of mothers is negatively associated with adherence to preventive healthcare visits among their children early in life. Future research is needed to elucidate the mechanisms of this association and to develop and implement family-based intervention strategies.
确定母婴童年期逆境经历(ACE)暴露与 2 岁以下儿童医疗保健利用之间的关联。
这是一项回顾性队列研究,对一家大型郊区儿科初级保健机构的 454 名患者进行了研究,其母亲(n=374)、父亲(n=156)或父母双方(n=123)在 2012 年 10 月至 2014 年 6 月期间完成了 ACE 调查。使用多变量负二项回归模型,对报告的父母 ACE 与 2 岁以下儿童医疗保健利用之间的关联进行建模,包括错过常规儿童保健就诊次数、就诊次数、延迟或错过免疫接种的次数。所有分析均调整了儿童性别、支付来源和早产。
母亲 ACE 暴露与 2 岁时的常规儿童保健就诊次数减少显著相关,但父亲 ACE 暴露无此关联。与每增加一个母亲 ACE 相关,常规儿童保健就诊次数减少的发生率显著增加 12%(相对风险,1.12;95%CI,1.03-1.22;P=.010)。母亲和父亲的 ACE 评分与就诊次数增加或免疫接种延迟或遗漏无关。
母亲 ACE 暴露与儿童生命早期遵行预防保健就诊率降低有关。未来需要进一步研究阐明这种关联的机制,并制定和实施以家庭为基础的干预策略。