Neves Washington Batista das, Brito Ana Maria de, Vasconcelos Andreza Pâmela, Melo Fárida Coeli de Barros Correia, Melo Raul Antônio Morais
Centro de Pesquisas Aggeu Magalhães (CPqAM), Recife, PE, Brazil; Fundação Hemope (HEMOPE), Recife, PE, Brazil.
Centro de Pesquisas Aggeu Magalhães (CPqAM), Recife, PE, Brazil.
Hematol Transfus Cell Ther. 2019 Jul-Sep;41(3):212-215. doi: 10.1016/j.htct.2018.08.009. Epub 2019 Mar 28.
The establishment of regional development poles in the State of Pernambuco, Brazil was characterized by industrial expansion and consequent concerns about the increase in the occurrence of diseases, specifically those having long latency periods, as is the case of Chronic Myeloid Leukemia.
The study included 367 patients diagnosed with Chronic Myeloid Leukemia over a ten-year period at a reference treatment center. Records of patient charts and the TerraView software were used, respectively, for data collection and geographic mapping of the cases from the twelve established State development regions.
A total incidence of 3.4 cases per 100,000 inhabitants was found, with a predominance of the disease among males, a median age of 47 years, a mestizo ethnicity, with elementary schooling and residence in urban area. Microregional incidence varied, but there was no significant variation in numbers over the years, and no relevant socio-environmental determinants were identified.
The present study determined the incidence and characterized the spatial distribution of Chronic Myeloid Leukemia cases over a decade in a northeastern Brazilian state. The variation in the incidence rate by region of development is compatible with a homogeneous distribution of the cases. The work is a baseline study to be used for present and future analyses of the impact of the state economic development poles and the occurrence of this chronic malignant disease.
巴西伯南布哥州区域发展极点的建立以工业扩张为特征，随之而来的是对疾病发生率上升的担忧，特别是那些潜伏期长的疾病，慢性髓性白血病就是这种情况。
该研究纳入了在一家参考治疗中心十年期间被诊断为慢性髓性白血病的367名患者。分别使用患者病历记录和TerraView软件，从该州已建立的十二个发展区域收集病例数据并进行地理绘图。
发现总发病率为每10万居民3.4例，男性患者居多，中位年龄为47岁，混血种族，接受小学教育，居住在城市地区。微观区域发病率有所不同，但多年来病例数没有显著变化，也未发现相关的社会环境决定因素。
本研究确定了巴西东北部一个州十年间慢性髓性白血病病例的发病率，并对其空间分布进行了特征描述。按发展区域划分的发病率差异与病例的均匀分布相符。这项工作是一项基线研究，可用于当前和未来对该州经济发展极点与这种慢性恶性疾病发生之间影响关系的分析。
