Callera Fernando, Brasil Alvaro Azevedo Vital, Casali Anna Raquel de Lima, Mulin Carla Cecília, Rosa Evandro Secchi, Barbosa Maira de Assis, Vieira Thais Domitila Freire
Grupo de Onco-hematologia do Vale do Paraíba - GOHV, São José dos Campos, SP, Brazil.
Rev Bras Hematol Hemoter. 2011;33(2):120-5. doi: 10.5581/1516-8484.20110032.
Based on the necessity of detailed information that supports effective strategies to improve cancer outcomes in the different regions of Brazil, the aims of this study were to report demographic aspects and to calculate the prevalence and incidence rates of oncohematological diseases in the region of Vale do Paraíba.
This is a multicentric prospective study carried out from October 2009 to March 2010. A total of 500 over 19-year-old patients were enrolled. Data such as type of healthcare insurance, gender, age, ethnic classification, place of residence, schooling, income, body mass index, new cases and the period between the first symptoms and a definite diagnosis were collected. The prevalence and incidence rates were calculated according to an estimated number of 1,319,800 inhabitants.
The prevalence and incidence rates per 100,000 inhabitants in the period of six months were, respectively: acute myeloid leukemia 1.5 and 0.7; acute lymphoblastic leukemia 0.5 and 0.1; chronic lymphocytic leukemia 2.4 and 0.4; chronic myeloid leukemia 6.2 and 0.8; Hodgkin's lymphoma 2.9 and 0.9; non-Hodgkin lymphoma 9.8 and 4.3; multiple myeloma 5.7 and 0.7; myelodysplastic syndromes 2.1 and 0.2 and myeloproliferative syndromes 5.1 and 0.3.
Giving the paucity of data in this field of investigation, our data may be useful for comparisons with those of other regions of Brazil and will assist in the implementation of treatment programs of oncohematological diseases in this region.
基于获取详细信息以支持改善巴西不同地区癌症治疗效果的有效策略的必要性，本研究旨在报告人口统计学方面的情况，并计算帕拉伊巴河谷地区血液肿瘤疾病的患病率和发病率。
这是一项于2009年10月至2010年3月开展的多中心前瞻性研究。共纳入500名19岁以上的患者。收集了诸如医疗保险类型、性别、年龄、种族分类、居住地点、受教育程度、收入、体重指数、新发病例以及首次出现症状至明确诊断之间的时间等数据。根据估计的1319800名居民数量计算患病率和发病率。
六个月期间每10万居民的患病率和发病率分别为：急性髓系白血病1.5和0.7；急性淋巴细胞白血病0.5和0.1；慢性淋巴细胞白血病2.4和0.4；慢性髓系白血病6.2和0.8；霍奇金淋巴瘤2.9和0.9；非霍奇金淋巴瘤9.8和4.3；多发性骨髓瘤5.7和0.7；骨髓增生异常综合征2.1和0.2；骨髓增殖性综合征5.1和0.3。
鉴于该研究领域数据匮乏，我们的数据可能有助于与巴西其他地区的数据进行比较，并将有助于在该地区实施血液肿瘤疾病的治疗方案。
