Anishchenko Ilya M, McCartney Mitchell M, Fung Alexander G, Peirano Daniel J, Schirle Michael J, Kenyon Nicholas J, Davis Cristina E
Department of Mechanical and Aerospace Engineering, University of California, Davis, One Shields Avenue, Davis, CA 95616, USA.
Department of Internal Medicine, University of California, 4150 V Street, Suite 3400, Davis, Sacramento, CA 95817, USA.
Int J Ion Mobil Spectrom. 2018 Dec;21(4):125-136. doi: 10.1007/s12127-018-0240-4. Epub 2018 Aug 31.
Due to the versatility of present day microcontroller boards and open source development environments, new analytical chemistry devices can now be built outside of large industry and instead within smaller individual groups. While there are a wide range of commercial devices available for detecting and identifying volatile organic compounds (VOCs), most of these devices use their own proprietary software and complex custom electronics, making modifications or reconfiguration of the systems challenging. The development of microprocessors for general use, such as the Arduino prototyping platform, now enables custom chemical analysis instrumentation. We have created an example system using commercially available parts, centered around on differential mobility spectrometer (DMS) device. The Modular Reconfigurable Gas Chromatography - Differential Mobility Spectrometry package (MR-GC-DMS) has swappable components allowing it to be quickly reconfigured for specific application purposes as well as broad, generic use. The MR-GC-DMS has a custom user-friendly graphical user interface (GUI) and precisely tuned proportional-integral-derivative controller (PID) feedback control system managing individual temperature-sensitive components. Accurate temperature control programmed into the microcontroller greatly increases repeatability and system performance. Together, this open-source platform enables researchers to quickly combine DMS devices in customized configurations for new chemical sensing applications.
由于当今微控制器开发板和开源开发环境的多功能性，新型分析化学设备现在可以在大型工业之外，而是在较小的个体团队中构建。虽然有各种各样的商业设备可用于检测和识别挥发性有机化合物（VOC），但这些设备大多使用自己的专有软件和复杂的定制电子设备，这使得对系统进行修改或重新配置具有挑战性。通用微处理器的开发，如Arduino原型平台，现在使得定制化学分析仪器成为可能。我们使用市售部件创建了一个示例系统，该系统以差分迁移谱仪（DMS）设备为核心。模块化可重构气相色谱 - 差分迁移谱仪套件（MR-GC-DMS）具有可互换的组件，使其能够针对特定应用目的以及广泛的通用用途进行快速重新配置。MR-GC-DMS有一个定制的用户友好图形用户界面（GUI）和精确调谐的比例积分微分控制器（PID）反馈控制系统，用于管理各个对温度敏感的组件。微控制器中编程的精确温度控制大大提高了可重复性和系统性能。总之，这个开源平台使研究人员能够快速将DMS设备以定制配置组合起来，用于新的化学传感应用。
