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大鼠弓状核神经元中人生长激素释放因子(hGHRF)和神经肽Y(NPY)免疫反应性的共存。

Coexistence of hGHRF and NPY immunoreactivities in neurons of the arcuate nucleus of the rat.

作者信息

Ciofi P, Croix D, Tramu G

出版信息

Neuroendocrinology. 1987 May;45(5):425-8. doi: 10.1159/000124769.

DOI:10.1159/000124769
PMID:3108692
Abstract

The distributions of perikarya exhibiting human somatocrinin (hGHRF) and neuropeptide Y (NPY) like immunoreactivities (IR) were compared in the arcuate nucleus of colchicine-treated rats. The majority of hGHRF perikarya was found to exhibit simultaneously NPY IR, while virtually no NPY IR was detected in the external layer of the median eminence. It is suggested that the majority of the hGHRF neurons of the rat arcuate nucleus constitutes a tubero-extra-infundibularly projecting system.

摘要

在秋水仙碱处理的大鼠弓状核中,比较了呈现人生长激素释放因子(hGHRF)和神经肽Y(NPY)样免疫反应性(IR)的核周体分布。发现大多数hGHRF核周体同时呈现NPY IR,而在正中隆起外层几乎未检测到NPY IR。提示大鼠弓状核的大多数hGHRF神经元构成一个结节-漏斗外投射系统。

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