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65岁以上骨质疏松症患者的诊断与治疗:现状与未来展望

[Diagnostics and treatment of osteoporosis in patients over 65 years old : Current status and future perspectives].

作者信息

Dovjak Peter

机构信息

Akutgeriatrie, Salzkammergutklinikum Gmunden, Miller-von-Aichholzstr. 49, 4810, Gmunden, Österreich.

出版信息

Z Gerontol Geriatr. 2019 Aug;52(5):421-427. doi: 10.1007/s00391-019-01548-w. Epub 2019 May 13.

Abstract

Only one third of all women with osteoporosis over the age of 65 years are adequately treated; therefore, many experience fractures. For men the data are insufficient. Using a newly developed algorithm and based on the current guidelines, the diagnosis and specific treatment of osteoporosis can be easily set up. The differential treatment should be selected in an individualized approach based on the side effect profile of the specific medication. No statistically significant differences were found between most specific osteoporotic drugs in head-to-head comparisons. This article presents an overview of the currently available pharmaceutical and non-pharmaceutical forms of treatment as well as approaches with novel medications and interventions for a better control of osteoporosis.

摘要

在65岁以上患有骨质疏松症的女性中,只有三分之一得到了充分治疗;因此,许多人会发生骨折。男性的数据不足。使用新开发的算法并基于当前指南,可以轻松建立骨质疏松症的诊断和具体治疗方法。应根据特定药物的副作用情况,以个体化方式选择差异治疗。在直接比较中,大多数特定的骨质疏松药物之间未发现统计学上的显著差异。本文概述了目前可用的药物和非药物治疗形式,以及使用新型药物和干预措施更好地控制骨质疏松症的方法。

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