Suppr超能文献

老年创伤患者骨质疏松症的调查与管理:一种适应德国骨质疏松症指南的治疗算法

Investigation and management of osteoporosis in aged trauma patients: a treatment algorithm adapted to the German guidelines for osteoporosis.

作者信息

Neuerburg Carl, Mittlmeier Lena, Schmidmaier Ralf, Kammerlander Christian, Böcker Wolfgang, Mutschler Wolf, Stumpf Ulla

机构信息

Department of General, Trauma and Reconstruction Surgery, Munich University Hospital LMU, Campus Großhadern, Marchioninistr. 15, 81377, Munich, Germany.

Department of Endocrinology, Medizinische Klinik und Poliklinik IV, Klinikum der Universität München, Munich, Germany.

出版信息

J Orthop Surg Res. 2017 Jun 8;12(1):86. doi: 10.1186/s13018-017-0585-0.

Abstract

BACKGROUND

Osteoporosis-associated fractures are of increasing importance in trauma surgery. Systematic diagnostics and treatment of osteoporosis during a hospital stay, however, remain inadequate. Therefore, a specific algorithm for diagnosing and treating osteoporosis in trauma surgery patients was developed based on the DVO (German Osteology Society) guideline for osteoporosis from 2014.

METHODS

In a first step, the individuals' age and risk profile for osteoporosis is identified considering specific fractures indicating osteoporosis and risk factors assessed by a specific questionnaire. In addition, physical activity, risk of falls, dietary habits and the individuals' medication are considered. Basic osteoporosis laboratory tests, a bone densitometry by dual-energy X-ray absorptiometry (DXA) and, if needed, X-rays of the spine are carried out to identify prevalent vertebral body fractures.

RESULTS

Based on the treatment algorithm adapted to the new guidelines for osteoporosis in the majority of proximal femoral fractures, treatment of osteoporosis could already be indicated without prior DXA. In case of preexisting glucocorticoid therapy, a history of previous fractures or other risk factors according to the risk questionnaire, the threshold of treatment has to be adjusted given the table of T-scores.

CONCLUSIONS

The treatment algorithm for diagnosing and treating osteoporosis in in-patient trauma surgery patients can help identify high-risk patients systematically and efficiently. As a result, osteoporosis-associated fractures or failure of osteosynthesis could be reduced, yet a prospective validation of the algorithm has to be completed.

摘要

背景

骨质疏松相关骨折在创伤外科中的重要性日益增加。然而,住院期间对骨质疏松的系统诊断和治疗仍然不足。因此,基于2014年德国骨科学会(DVO)的骨质疏松指南,制定了一种针对创伤外科患者骨质疏松的诊断和治疗的特定算法。

方法

第一步,考虑表明骨质疏松的特定骨折以及通过特定问卷评估的风险因素,确定个体的年龄和骨质疏松风险状况。此外,还要考虑身体活动、跌倒风险、饮食习惯和个体用药情况。进行基本的骨质疏松实验室检查、双能X线吸收法(DXA)骨密度测定,必要时进行脊柱X线检查,以确定是否存在椎体骨折。

结果

基于适用于大多数股骨近端骨折骨质疏松新指南的治疗算法,在未进行DXA检查之前即可指示进行骨质疏松治疗。如果存在糖皮质激素治疗史、既往骨折史或根据风险问卷的其他风险因素,则必须根据T值表调整治疗阈值。

结论

住院创伤外科患者骨质疏松的诊断和治疗算法有助于系统且高效地识别高危患者。因此,可减少骨质疏松相关骨折或骨合成失败的情况,但该算法仍需进行前瞻性验证。

文献检索

告别复杂PubMed语法,用中文像聊天一样搜索,搜遍4000万医学文献。AI智能推荐,让科研检索更轻松。

立即免费搜索

文件翻译

保留排版,准确专业,支持PDF/Word/PPT等文件格式,支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述,25分钟生成高质量综述,智能提取关键信息,辅助科研写作。

立即免费体验