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预先护理计划对临终关怀的影响:对于转诊至临终关怀机构的晚期癌症患者,其类型和时机是否有所不同?

The Impact of Advance Care Planning on End-of-Life Care: Do the Type and Timing Make a Difference for Patients With Advanced Cancer Referred to Hospice?

作者信息

Prater Laura C, Wickizer Thomas, Bower Julie K, Bose-Brill Seuli

机构信息

1 Department of General Internal Medicine, The Ohio State University Wexner Medical Center, Columbus, OH, USA.

2 The Ohio State University College of Public Health, Columbus, OH, USA.

出版信息

Am J Hosp Palliat Care. 2019 Dec;36(12):1089-1095. doi: 10.1177/1049909119848987. Epub 2019 May 14.

Abstract

PURPOSE

This study aimed to determine the impact of advanced care planning (ACP) on potentially avoidable hospital admissions at the end of life (EOL) among a sample of hospice-referred patients with cancer, in order to present actionable considerations for the practicing clinician.

METHODS

This study was designed as a retrospective cohort using electronic health record data that assessed likelihood of hospital admissions in the last 30 days of life for 1185 patients with a primary diagnosis of cancer, referred to hospice between January 1, 2014, and December 31, 2015, at a large academic medical center. Inverse probability treatment weighting based on calculated propensity scores balanced measured covariates between those with and without ACP at baseline. Odds ratios (ORs) were calculated from estimated potential outcome means for the impact of ACP on admissions in the last 30 days of life.

RESULTS

A verified do-not-resuscitate (DNR) order prior to the last 30 days of life was associated with reduced odds of admission compared to those without a DNR (OR = 0.30; < .001). An ACP note in the problem list prior to the last 30 days of life was associated with reduced odds of admission compared to those without an ACP note (OR = 0.71, = .042), and further reduced odds if done 6 months prior to death (OR = 0.35, < .001).

CONCLUSIONS

This study shows that dedicated ACP documentation is associated with fewer admissions in the last 30 days of life for patients with advanced cancer referred to hospice. Improving ACP processes prior to hospice referral holds promise for reducing EOL admissions.

摘要

目的

本研究旨在确定预先护理计划(ACP)对临终关怀机构转介的癌症患者样本在生命末期(EOL)可能避免的住院情况的影响,以便为临床医生提供可操作的考虑因素。

方法

本研究设计为回顾性队列研究,使用电子健康记录数据评估了2014年1月1日至2015年12月31日期间在一家大型学术医疗中心被转介至临终关怀机构的1185例原发性癌症患者在生命最后30天内的住院可能性。基于计算出的倾向得分进行逆概率处理加权,平衡了基线时接受和未接受ACP患者之间的测量协变量。计算了优势比(OR),以估计ACP对生命最后30天内住院情况影响的潜在结果均值。

结果

与没有“不要复苏”(DNR)医嘱的患者相比,在生命最后30天之前有有效的DNR医嘱与住院几率降低相关(OR = 0.30;P <.001)。与没有ACP记录的患者相比,在生命最后30天之前问题列表中有ACP记录与住院几率降低相关(OR = 0.71,P =.042),如果在死亡前6个月进行则住院几率进一步降低(OR = 0.35,P <.001)。

结论

本研究表明,对于转介至临终关怀机构的晚期癌症患者,专门的ACP记录与生命最后30天内较少的住院情况相关。在临终关怀转介之前改善ACP流程有望减少EOL住院情况。

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