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Strategies to promote the maturation of ALS-associated SOD1 mutants: small molecules return to the fold.

作者信息

McAlary Luke, Yerbury Justin J

机构信息

Illawarra Health and Medical Research Institute, Wollongong; School of Chemistry and Molecular Bioscience, Molecular Horizons, Faculty of Science, Medicine and Health, University of Wollongong, NSW, Australia.

出版信息

Neural Regen Res. 2019 Sep;14(9):1511-1512. doi: 10.4103/1673-5374.255962.

DOI:10.4103/1673-5374.255962
PMID:31089043
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC6557088/
Abstract
摘要
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/b88f/6557088/370cf84c37db/NRR-14-1511-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/b88f/6557088/370cf84c37db/NRR-14-1511-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/b88f/6557088/370cf84c37db/NRR-14-1511-g001.jpg

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Neurobiol Dis. 2019 Apr;124:297-310. doi: 10.1016/j.nbd.2018.11.025. Epub 2018 Dec 4.
2
CuATSM Protects Against the In Vitro Cytotoxicity of Wild-Type-Like Copper-Zinc Superoxide Dismutase Mutants but not Mutants That Disrupt Metal Binding.CuATSM 可防止类似野生型的铜锌超氧化物歧化酶突变体的体外细胞毒性,但不能防止破坏金属结合的突变体。
ACS Chem Neurosci. 2019 Mar 20;10(3):1555-1564. doi: 10.1021/acschemneuro.8b00527. Epub 2018 Dec 7.
3
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Pharmaceuticals (Basel). 2024 Sep 27;17(10):1286. doi: 10.3390/ph17101286.
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Nat Commun. 2018 Apr 27;9(1):1693. doi: 10.1038/s41467-018-04114-x.
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