电休克治疗对促甲状腺激素释放激素刺激试验的影响。

Effects of ECT on the TRH stimulation test.

作者信息

Decina P, Sackeim H A, Kahn D A, Pierson D, Hopkins N, Malitz S

出版信息

Psychoneuroendocrinology. 1987;12(1):29-34. doi: 10.1016/0306-4530(87)90019-9.

Abstract

The prognostic value of the TRH stimulation test was evaluated in 23 inpatients with major depressive disorder before and after a trial of ECT. In contrast to previous reports, the peak TSH response to TRH was significantly decreased after treatment compared with before treatment. This effect was consistent across individuals and subgroups (responders/nonresponders; unilateral/bilateral ECT). The particular ECT technique used in the study may account for the discrepancies between these findings and those previously reported by other authors.

摘要

对23例重度抑郁症住院患者在进行电休克治疗（ECT）试验前后进行促甲状腺激素释放激素（TRH）刺激试验，以评估其预后价值。与之前的报告相反，治疗后TRH刺激试验中促甲状腺激素（TSH）的峰值反应较治疗前显著降低。这种效应在个体和亚组（反应者/无反应者；单侧/双侧ECT）中是一致的。该研究中使用的特定ECT技术可能解释了这些结果与其他作者先前报告结果之间的差异。