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南亚高血压和痴呆症的挑战:综述。

Challenges of hypertension and dementia in the Indian subcontinent: a review.

机构信息

Department of Cardiology, PRS Hospital, Trivandrum, Kerala, 695002, India.

出版信息

J Hum Hypertens. 2019 Aug;33(8):568-574. doi: 10.1038/s41371-019-0205-z. Epub 2019 May 14.

DOI:10.1038/s41371-019-0205-z
PMID:31089200
Abstract

Hypertension is regarded as a major contributor to vascular disease. Vascular disease is a fairly common denominator in a large percentage of cases of dementia. Despite this strong connecting link, dementia is often not considered as a mainstream problem consequent to hypertension, though there is an alarming increase in the number of cases of dementia. While established dementia has very few treatment options, prevention of development and slowing of progression of dementia by proper treatment of hypertension could be an important strategy, especially so, in a financially challenged Indian subcontinent with inhomogeneous health coverage. None of us wants to be reminded that dementia is random, relentless, and frighteningly common-Laurie Graham.

摘要

高血压被认为是血管疾病的主要诱因。血管疾病在很大比例的痴呆病例中是一个相当常见的共同因素。尽管存在这种紧密的关联,但痴呆症通常不被认为是高血压的主要问题,尽管痴呆症的病例数量正在惊人地增加。虽然已经确定的痴呆症治疗选择非常有限,但通过适当治疗高血压来预防痴呆症的发展和减缓其进展可能是一个重要策略,特别是在财政困难的、医疗保障不均衡的印度次大陆。我们都不希望被提醒痴呆症是随机的、无情的,而且非常普遍——劳里·格雷厄姆。

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本文引用的文献

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Effect of Intensive vs Standard Blood Pressure Control on Probable Dementia: A Randomized Clinical Trial.强化与标准血压控制对可能发生的痴呆的影响:一项随机临床试验。
JAMA. 2019 Feb 12;321(6):553-561. doi: 10.1001/jama.2018.21442.
2
25-Year trends in hypertension prevalence, awareness, treatment, and control in an Indian urban population: Jaipur Heart Watch.印度城市人口中高血压患病率、知晓率、治疗率和控制率的25年趋势:斋浦尔心脏观察
Indian Heart J. 2018 Nov-Dec;70(6):802-807. doi: 10.1016/j.ihj.2017.11.011. Epub 2017 Nov 13.
3
Hypertension: The most important non communicable disease risk factor in India.
Spotlight on hypertension in the Indian subcontinent.
聚焦印度次大陆的高血压问题。
J Hum Hypertens. 2019 Aug;33(8):559-561. doi: 10.1038/s41371-019-0216-9. Epub 2019 Jul 3.
高血压:印度最重要的非传染性疾病风险因素。
Indian Heart J. 2018 Jul-Aug;70(4):565-572. doi: 10.1016/j.ihj.2018.02.003. Epub 2018 Feb 12.
4
Global and regional effects of potentially modifiable risk factors associated with acute stroke in 32 countries (INTERSTROKE): a case-control study.32 个国家与急性脑卒中相关的可改变潜在风险因素的全球和区域效应(INTERSTROKE):病例对照研究。
Lancet. 2016 Aug 20;388(10046):761-75. doi: 10.1016/S0140-6736(16)30506-2. Epub 2016 Jul 16.
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Is hypertension associated with an accelerated aging of the brain?高血压是否与大脑加速衰老有关?
Hypertension. 2014 May;63(5):894-903. doi: 10.1161/HYPERTENSIONAHA.113.00147. Epub 2014 Feb 24.
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Hypertension: a harbinger of stroke and dementia.高血压:中风和痴呆的先兆。
Hypertension. 2013 Nov;62(5):810-7. doi: 10.1161/HYPERTENSIONAHA.113.01063. Epub 2013 Aug 26.
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Hypertension and cognitive functioning: a perspective in historical context.高血压与认知功能:历史背景下的视角
Hypertension. 2012 Aug;60(2):260-8. doi: 10.1161/HYPERTENSIONAHA.111.186429. Epub 2012 Jul 2.
8
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Hypertens Res. 2011 Jan;34(1):120-5. doi: 10.1038/hr.2010.192. Epub 2010 Oct 21.
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J Hypertens. 2010 Oct;28(10):2036-45. doi: 10.1097/HJH.0b013e32833b49fe.
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