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Hypertension: a harbinger of stroke and dementia.高血压：中风和痴呆的先兆。
Hypertension. 2013 Nov;62(5):810-7. doi: 10.1161/HYPERTENSIONAHA.113.01063. Epub 2013 Aug 26.
2
Leukoaraiosis: the brain under pressure: target for treatment?脑白质疏松症：处于压力下的大脑：治疗靶点？
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[Hypertension and the brain].[高血压与大脑]
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Blood pressure and treatment of persons with hypertension as it relates to cognitive outcomes including executive function.血压与高血压患者的治疗及其与包括执行功能在内的认知结果的关系。
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Perspective: silent, but preventable, perils.观点：无声却可预防的危险。
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Hypertension and Dementia: Epidemiological and Experimental Evidence Revealing a Detrimental Relationship.高血压与痴呆症：揭示有害关系的流行病学和实验证据
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Visit-to-visit blood pressure variability and dementia.就诊间血压变异性与痴呆症
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Preventing dementia by treating hypertension and preventing stroke.通过治疗高血压和预防中风来预防痴呆症。
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Early brain damage in essential hypertension: "to have and have not"--is it important?原发性高血压早期脑损伤：“有与无”——这重要吗？
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Pharmacoepigenomic Impact of Antihypertensive Drugs on miRNome and Proteome and Its Potential Influence on Health and Side Effects.抗高血压药物对微小RNA组和蛋白质组的药物表观基因组学影响及其对健康和副作用的潜在影响。
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Hypertension, intracranial arteriosclerosis, and structural brain changes in patients with TIA or ischemic stroke.短暂性脑缺血发作（TIA）或缺血性卒中患者的高血压、颅内动脉硬化和脑结构改变。
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Models and mechanisms of post-stroke dementia and cognitive impairment.中风后痴呆和认知障碍的模型与机制
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4
Association of circulating Notch1 and VEGF with flow-mediated dilation and aerobic fitness in healthy adults.健康成年人循环Notch1和VEGF与血流介导的血管舒张及有氧适能的关联
Transl Exerc Biomed. 2025 May 28;2(2):74-82. doi: 10.1515/teb-2025-0006. eCollection 2025 Jul.
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Research on ischemic stroke risk assessment based on CTA radiomics and machine learning.基于CTA影像组学和机器学习的缺血性中风风险评估研究
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Electrolyte Levels in Poor Prognosis and Early Neurological Deterioration in Patients With Acute Ischemic Stroke.急性缺血性脑卒中患者预后不良及早期神经功能恶化时的电解质水平
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Effect of amphetamines on blood pressure.安非他命对血压的影响。
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Sex-Specific Adaptations in Alzheimer's Disease and Ischemic Stroke: A Longitudinal Study in Male and Female APP/PS1 Mice.阿尔茨海默病和缺血性中风中的性别特异性适应：对雄性和雌性APP/PS1小鼠的纵向研究
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Association between atherosclerosis and the development of multi-organ pathologies.动脉粥样硬化与多器官病变发展之间的关联。
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Baroreflex Sensitivity and Long-Term Dementia Risk in Older Adults.老年人压力反射敏感性与长期痴呆风险
Hypertension. 2025 Feb;82(2):347-356. doi: 10.1161/HYPERTENSIONAHA.124.24001. Epub 2024 Dec 13.

本文引用的文献

1
Multimodal imaging in rats reveals impaired neurovascular coupling in sustained hypertension.多模态成像技术在大鼠中揭示了持续性高血压中的神经血管耦联受损。
Stroke. 2013 Jul;44(7):1957-64. doi: 10.1161/STROKEAHA.111.000185. Epub 2013 Jun 4.
2
Mechanisms of sporadic cerebral small vessel disease: insights from neuroimaging.散发性脑小血管病的发病机制：神经影像学的启示。
Lancet Neurol. 2013 May;12(5):483-97. doi: 10.1016/S1474-4422(13)70060-7.
3
Risk factors for β-amyloid deposition in healthy aging: vascular and genetic effects.健康衰老中β-淀粉样蛋白沉积的风险因素：血管和遗传效应。
JAMA Neurol. 2013 May;70(5):600-6. doi: 10.1001/jamaneurol.2013.1342.
4
Intensive blood pressure lowering increases cerebral blood flow in older subjects with hypertension.强化降压增加老年高血压患者的脑血流。
Hypertension. 2013 Jun;61(6):1309-15. doi: 10.1161/HYPERTENSIONAHA.112.200972. Epub 2013 Mar 25.
5
High blood pressure and cerebral white matter lesion progression in the general population.高血压与普通人群的脑白质病变进展。
Hypertension. 2013 Jun;61(6):1354-9. doi: 10.1161/HYPERTENSIONAHA.111.00430. Epub 2013 Mar 25.
6
Estimating cerebral microinfarct burden from autopsy samples.从尸检样本估算脑微梗死负担。
Neurology. 2013 Apr 9;80(15):1365-9. doi: 10.1212/WNL.0b013e31828c2f52. Epub 2013 Mar 13.
7
Innate immunity receptor CD36 promotes cerebral amyloid angiopathy.先天免疫受体 CD36 促进脑淀粉样血管病。
Proc Natl Acad Sci U S A. 2013 Feb 19;110(8):3089-94. doi: 10.1073/pnas.1300021110. Epub 2013 Feb 4.
8
The treatment of hypertension: a remarkable success story.高血压治疗：一个显著的成功案例。
J Clin Hypertens (Greenwich). 2013 Feb;15(2):88-91. doi: 10.1111/jch.12033. Epub 2012 Nov 26.
9
Effects of angiotensin II on the cerebral circulation: role of oxidative stress.血管紧张素 II 对脑循环的影响：氧化应激的作用。
Front Physiol. 2013 Jan 3;3:484. doi: 10.3389/fphys.2012.00484. eCollection 2012.
10
Oligodendrocyte precursors induce early blood-brain barrier opening after white matter injury.少突胶质前体细胞在白质损伤后诱导早期血脑屏障开放。
J Clin Invest. 2013 Feb;123(2):782-6. doi: 10.1172/JCI65863. Epub 2013 Jan 2.

Hypertension: a harbinger of stroke and dementia.

作者信息

Faraco Giuseppe, Iadecola Costantino

机构信息

Brain and Mind Research Institute, Weill Cornell Medical College, 407 E 61st St, RR-303, New York, NY 10065.

出版信息

Hypertension. 2013 Nov;62(5):810-7. doi: 10.1161/HYPERTENSIONAHA.113.01063. Epub 2013 Aug 26.

DOI:10.1161/HYPERTENSIONAHA.113.01063
PMID:23980072
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC3847558/
Abstract
摘要