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自体髂嵴骨移植骨增量术后的创口裂开:一项回顾性队列研究。

Wound dehiscences following pre-implant bone augmentation with autogenous iliac crest bone grafts: A retrospective cohort study.

出版信息

Int J Oral Implantol (Berl). 2019;12(2):227-236.

PMID:31090752
Abstract

PURPOSE

To evaluate possible risk factors associated with wound dehiscences following pre-implant alveolar bone augmentation with autologous anterior iliac crest bone grafts covered with resorbable collagen membranes or human demineralised bone laminae.

MATERIALS AND METHODS

Data of 161 patients who underwent bone augmentation prior to the insertion of dental implants were analysed. The preoperative dental status, locations of alveolar bone augmentation sites and location of wound dehiscences were recorded. Gender, age, smoking, alcohol exposure, and dental and medical histories were reviewed. Information was also collected on the surgeons, augmentation technique, application of a collagen membrane, fixation screw type and suture material. Univariate logistic regression analysis was used to evaluate pre- and perioperative variables as predictors of dehiscences.

RESULTS

A total of 42 (26.1%) of the 161 augmented patients developed a wound dehiscence following surgery. Most commonly affected sites were the anterior maxilla, followed by the anterior mandible. Males developed wound dehiscences with higher probability than females (odds ratio female = 0.444; P = 0.025; 95% CI: 0.214 to 0.903). Furthermore, marginal associations (P < 0.10) are found for smoking and an anterior location of the augmentation. Smokers were found to have higher probability of a wound dehiscence (odds ratio 2.089; P = 0.064; 95% CI: 0.957 to 4.500) compared to non-smokers. A posterior location of the augmentation was associated with lower probability of a wound dehiscence (odds ratio 0.188; P = 0.076; 95% CI: 0.035 to 0.802) compared to an anterior location.

CONCLUSIONS

Based on this study population, smoking in males seems to be the most important risk factor for the development of wound dehiscences after pre-implant alveolar bone augmentation procedures.

摘要

目的

评估与使用自体髂前嵴骨移植物覆盖可吸收胶原膜或人脱矿骨片行植入前牙槽骨增量后伤口裂开相关的可能风险因素。

材料和方法

分析了 161 名接受骨增量术以植入牙种植体的患者的数据。记录了术前的口腔状况、牙槽骨增量部位的位置以及伤口裂开的位置。评估了性别、年龄、吸烟、饮酒、牙科和医疗史。还收集了外科医生、增量技术、胶原膜的应用、固定螺钉类型和缝线材料的信息。使用单变量逻辑回归分析评估了术前和围手术期变量作为伤口裂开的预测因子。

结果

161 名接受骨增量术的患者中,共有 42 名(26.1%)术后出现伤口裂开。最常受累的部位是前上颌骨,其次是前下颌骨。男性比女性更有可能发生伤口裂开(女性比值比=0.444;P=0.025;95%可信区间:0.214 至 0.903)。此外,吸烟和增量部位在前的情况存在边缘相关性(P<0.10)。与不吸烟者相比,吸烟者发生伤口裂开的概率更高(比值比 2.089;P=0.064;95%可信区间:0.957 至 4.500)。与前位增量相比,后位增量与伤口裂开的低概率相关(比值比 0.188;P=0.076;95%可信区间:0.035 至 0.802)。

结论

根据本研究人群,男性吸烟似乎是植入前牙槽骨增量术后伤口裂开的最重要危险因素。

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