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一次性传感器在诊断、食品和环境监测中的应用。

Disposable Sensors in Diagnostics, Food, and Environmental Monitoring.

机构信息

Department of Bioengineering, Imperial College London, Royal School of Mines, SW7 2AZ, London, UK.

University of Freiburg, Freiburg Center for Interactive Materials and Bioinspired Technologies (FIT), 79110, Freiburg, Germany.

出版信息

Adv Mater. 2019 Jul;31(30):e1806739. doi: 10.1002/adma.201806739. Epub 2019 May 15.

DOI:10.1002/adma.201806739
PMID:31094032
Abstract

Disposable sensors are low-cost and easy-to-use sensing devices intended for short-term or rapid single-point measurements. The growing demand for fast, accessible, and reliable information in a vastly connected world makes disposable sensors increasingly important. The areas of application for such devices are numerous, ranging from pharmaceutical, agricultural, environmental, forensic, and food sciences to wearables and clinical diagnostics, especially in resource-limited settings. The capabilities of disposable sensors can extend beyond measuring traditional physical quantities (for example, temperature or pressure); they can provide critical chemical and biological information (chemo- and biosensors) that can be digitized and made available to users and centralized/decentralized facilities for data storage, remotely. These features could pave the way for new classes of low-cost systems for health, food, and environmental monitoring that can democratize sensing across the globe. Here, a brief insight into the materials and basics of sensors (methods of transduction, molecular recognition, and amplification) is provided followed by a comprehensive and critical overview of the disposable sensors currently used for medical diagnostics, food, and environmental analysis. Finally, views on how the field of disposable sensing devices will continue its evolution are discussed, including the future trends, challenges, and opportunities.

摘要

一次性传感器是低成本、易于使用的传感设备,旨在进行短期或快速单点测量。在这个互联互通的世界中,人们对快速、可访问和可靠信息的需求不断增长,这使得一次性传感器变得越来越重要。此类设备的应用领域非常广泛,包括制药、农业、环境、法医和食品科学到可穿戴设备和临床诊断,特别是在资源有限的环境中。一次性传感器的功能不仅可以测量传统的物理量(例如温度或压力);它们还可以提供关键的化学和生物信息(化学和生物传感器),这些信息可以数字化并提供给用户和集中/分散式设施,以便远程存储数据。这些功能可能为医疗、食品和环境监测领域的新型低成本系统铺平道路,从而在全球范围内实现传感的民主化。本文简要介绍了传感器的材料和基础知识(转换方法、分子识别和放大),然后全面而批判性地综述了目前用于医疗诊断、食品和环境分析的一次性传感器。最后,讨论了一次性传感设备领域将如何继续发展,包括未来的趋势、挑战和机遇。

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