Cavagnaro Sm Felipe
Clínica Alemana de Santiago, Facultad de Medicina, Universidad del Desarrollo, Chile.
Rev Chil Pediatr. 2019 Apr;90(2):139-144. doi: 10.32641/rchped.v90i2.1044.
Hemolytic uremic syndrome (HUS) associated with intestinal infection by Shiga toxin-producing bacteria, which mainly affects children, can cause severe acute morbidity, chronic sequelae in seve ral organs, and premature death in some of them. Given its zoonotic nature, adequate measures of agricultural management and proper hygiene of what we consume are essential to prevent infection. Once the HUS is triggered, medical management is currently mainly supportive. In recent years, va rious therapeutic strategies have been developed to prevent this disease from occurring or, at least, to mitigate its morbidity and mortality consequences. This article describes specific actions at different levels of prevention of this pathology.
溶血性尿毒症综合征(HUS)与产志贺毒素细菌引起的肠道感染有关,主要影响儿童,可导致严重的急性发病、多个器官的慢性后遗症,部分患者还会过早死亡。鉴于其人畜共患的性质,采取适当的农业管理措施和注意所食用食物的卫生对于预防感染至关重要。一旦引发HUS,目前的医疗管理主要是支持性的。近年来,已开发出各种治疗策略来预防这种疾病的发生,或者至少减轻其发病和死亡后果。本文描述了针对这种病症在不同预防层面的具体行动。