Wang Wen Jie, Cao Zong Xun, Feng Shun Yi, Song Ya Qi, Zhang Su Li, Bai Wen Jing, Li Yong
Emergency Department, Cangzhou Central Hospital, Cangzhou, China.
Medicine (Baltimore). 2019 May;98(20):e15702. doi: 10.1097/MD.0000000000015702.
This study aimed to investigate the prognostic predictive value of the platelet-lymphocyte ratio (PLR) in patients with acute paraquat (PQ) intoxication.A total of 107 patients with acute PQ intoxication via oral ingestion were admitted in Cangzhou Central Hospital from May 2012 to September 2018. Valuable detection indices were screened out by using Cox proportional hazard regression and receiver operating characteristic (ROC) curve analyses, and their diagnostic efficiency was evaluated by using Kaplan-Meier curve.The 90-day mortality was 58.9% (63/107). The Kaplan-Meier curve showed that PLR was not associated with 90-day survival (log-rank test; P = .661). In Cox proportional hazard regression analyses, PLR was not an independent risk factor. Meanwhile, the ROC curves showed that PLR had an AUC value of 0.569 (95% confidence interval: 0.459-0.679, P = .227) in predicting 90-day survival.PLR is not a prognostic predictor for patients with acute PQ intoxication.
本研究旨在探讨血小板-淋巴细胞比值(PLR)对急性百草枯(PQ)中毒患者的预后预测价值。2012年5月至2018年9月,沧州市中心医院共收治了107例经口摄入急性PQ中毒的患者。通过Cox比例风险回归和受试者工作特征(ROC)曲线分析筛选出有价值的检测指标,并采用Kaplan-Meier曲线评估其诊断效能。90天死亡率为58.9%(63/107)。Kaplan-Meier曲线显示,PLR与90天生存率无关(对数秩检验;P = 0.661)。在Cox比例风险回归分析中,PLR不是独立危险因素。同时,ROC曲线显示,PLR在预测90天生存率时的AUC值为0.569(95%置信区间:0.459 - 0.679,P = 0.227)。PLR不是急性PQ中毒患者的预后预测指标。