Mills Anne M, Shanes Elisheva D
Department of Pathology, University of Virginia, PO Box 800214, 1215 Lee Street, Charlottesville, VA 22908, USA.
Department of Pathology, University of Virginia, PO Box 800214, 1215 Lee Street, Charlottesville, VA 22908, USA.
Surg Pathol Clin. 2019 Jun;12(2):565-585. doi: 10.1016/j.path.2019.01.008.
Ovarian mucinous tumors range from benign cystadenomas to borderline tumors to frankly malignant adenocarcinomas, and may display either intestinal-type morphology or, less frequently, endocervical-type differentiation. The latter category has been the subject of recent controversy owing to its morphologic overlap with so-called "seromucinous" ovarian tumors, a group that shares more molecular features with endometrioid tumors than it does with either serous or mucinous ovarian neoplasias. Endocervical-type differentiation in ovarian mucinous tumors may also represent an endocervical metastasis. Distinction of primary ovarian mucinous tumors from gastrointestinal metastases can be difficult, as the morphology of intestinal-type ovarian mucinous primaries sometimes differs only subtly if at all from gastrointestinal metastases.
卵巢黏液性肿瘤范围从良性囊腺瘤到交界性肿瘤再到明显恶性的腺癌，可表现为肠型形态，或较少见的子宫颈内膜型分化。后一类肿瘤由于其形态学与所谓的“浆液黏液性”卵巢肿瘤重叠，近来一直存在争议，该组肿瘤与子宫内膜样肿瘤共享的分子特征比与浆液性或黏液性卵巢肿瘤更多。卵巢黏液性肿瘤中的子宫颈内膜型分化也可能代表子宫颈转移。区分原发性卵巢黏液性肿瘤与胃肠道转移瘤可能很困难，因为肠型原发性卵巢黏液性肿瘤的形态有时与胃肠道转移瘤仅存在细微差异，甚至毫无差异。
